FL115 for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new treatment called FL115 for individuals with advanced solid tumors. The main goal is to determine if FL115 is safe and tolerable for those whose cancers have not responded to standard therapies, such as immune checkpoint inhibitors. As an early-phase study, it is among the first times this treatment is tested in humans. The trial seeks participants with cancer that cannot be removed or cured with existing treatments and who have experienced tumor growth despite trying other options. As a Phase 1 trial, participants will be among the first to receive this new treatment, aiding researchers in understanding its effects in people.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, it mentions that you should not have had major surgery, chemotherapy, immunotherapy, or radiation therapy within 14 days before starting the study treatment. It's best to discuss your specific medications with the study team.
Is there any evidence suggesting that FL115 is likely to be safe for humans?
Research has shown that FL115 was safe in earlier studies, including those on bladder cancer. Although this is the first time FL115 is being tested in humans, past research suggests it is generally well-tolerated when used alone. It is important to remember that this treatment remains in the early testing stages, so researchers are primarily assessing its safety for people. Overall, early results are promising, indicating that FL115 could be a safe option for patients, but more research is needed to fully understand its safety and effects.12345
Why do researchers think this study treatment might be promising?
FL115 is unique because it introduces a novel mechanism of action targeting cancer cells differently than traditional chemotherapy or radiation treatments. Unlike existing options that often attack both healthy and cancerous cells indiscriminately, FL115 is designed to selectively target and inhibit specific proteins involved in cancer cell growth. This precision aims to reduce side effects and improve treatment effectiveness, making researchers optimistic about its potential impact on patient outcomes.
What evidence suggests that FL115 might be an effective treatment for advanced solid tumors?
Research has shown that FL115 delivers promising results in early cancer treatment studies. FL115, a new type of medicine, boosts the immune system to help fight cancer. Patients using FL115 experienced good safety outcomes and some early positive responses, indicating potential effectiveness for certain cancers. Specifically, FL115 was tested in patients with nonmuscle-invasive bladder cancer (NMIBC) and demonstrated positive results in safety and effectiveness. These early findings suggest that FL115 could be a promising option for patients with advanced solid tumors.35678
Are You a Good Fit for This Trial?
This trial is for adults over 18 with advanced solid tumors that haven't responded to standard treatments, including checkpoint inhibitors. Participants must have a measurable tumor or disease, be in relatively good health (ECOG status 0 or 1), and expect to live at least another six months. They need proper liver, kidney, and blood function and agree to use effective contraception.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive FL115 on Days 1, 8, 15, and 22 of each cycle to assess dose-limiting toxicity and monitor for adverse events
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- FL115
Find a Clinic Near You
Who Is Running the Clinical Trial?
Suzhou Forlong Biotechnology Co.,Ltd,
Lead Sponsor