This trial is testing a new medication to see if it is safe and tolerated by people with a certain medical condition.
- Glycogen Storage Disease
1 Primary · 15 Secondary · Reporting Duration: Pre-infusion, at mid-infusion, and at EOI on Day 1 up to Week 52
1 Treatment Group
1 of 1
18 Total Participants · 1 Treatment Group
Primary Treatment: mRNA-3745 · No Placebo Group · Phase 1
Who is running the clinical trial?
Age 18+ · All Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
- Cao, Jingsong, Minjung Choi, Eleonora Guadagnin, Maud Soty, Marine Silva, Vincent Verzieux, Edward Weisser, et al.. 2021. “Mrna Therapy Restores Euglycemia and Prevents Liver Tumors in Murine Model of Glycogen Storage Disease”. Nature Communications. Springer Science and Business Media LLC. doi:10.1038/s41467-021-23318-2.
- 2022. "A Study of mRNA-3745 in Participants With Glycogen Storage Disease Type 1a (GSD1a)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05095727.
Frequently Asked Questions
Are there still vacancies within this research endeavor for participants?
"According to the records posted on clinicaltrials.gov, patient recruitment for this medical trial is ongoing and open. This study was made public on June 1st 2022 and underwent its last modification November 21st of the same year." - Anonymous Online Contributor
How many healthcare facilities are actively conducting this research?
"Currently, 6 clinical sites are recruiting individuals for this trial. These locations include New York, Cincinnati and Houston plus 3 additional places. To reduce the necessary travel, it is beneficial to pick a site which is closest to your residence." - Anonymous Online Contributor
What risks do patients incur when taking mRNA-3745?
"The safety of mRNA-3745, which is currently the subject of a Phase 1 trial with limited data for both efficacy and safety, has been rated at level one." - Anonymous Online Contributor
How many participants are actively involved in this research study?
"For the successful completion of this clinical trial, 18 patients must meet its eligibility criteria. The sponsor is ModernaTX Inc., and they are running the study out of two renowned healthcare institutions: Columbia University Medical Center in New York City, and Cincinnati Children's Hospital Medical Center in Ohio." - Anonymous Online Contributor