Probiotics for Women's Health

AJ
FC
Overseen ByFaith C Adams, BSc
Age: 18 - 65
Sex: Female
Trial Phase: Phase 1
Sponsor: McMaster University

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether probiotics can enhance brain flexibility and balance estrogen in women, potentially improving mood and memory. Participants will take either a real probiotic (Progressive Perfect Probiotic) or a placebo (a look-alike pill with no active ingredients) for 28 days. The trial seeks right-handed women, ages 18 to 35, who have regular menstrual cycles and do not use hormone-based birth control. As a Phase 1 trial, the research focuses on understanding how the treatment works in people, offering participants the opportunity to be among the first to receive this innovative probiotic treatment.

Do I need to stop taking my current medications for the trial?

The trial does not specify if you need to stop taking your current medications, but it does exclude women who use hormone-altering devices like oral contraceptives.

Is there any evidence suggesting that this treatment is likely to be safe for humans?

Research has shown that probiotics have been used safely for many years. Although studies do not always report safety results consistently, probiotics generally have a good safety record. The Progressive Perfect Probiotic used in this study contains a mix of beneficial bacteria commonly found in other probiotic products for digestive and urinary health.

This early-stage trial primarily examines how well participants can tolerate the treatment. The probiotic strains used here are common in many health supplements, suggesting they are likely well-tolerated by most people. However, participants should consider any personal allergies or food sensitivities before joining. Always review product details if specific health concerns exist.12345

Why do researchers think this study treatment might be promising?

Unlike many traditional treatments for women's health that might rely on pharmaceuticals or hormones, Progressive Perfect Probiotic is unique because it harnesses the power of probiotics to potentially improve health outcomes. This probiotic contains an impressive 120 billion CFUs with a diverse blend of beneficial strains like Lactobacillus plantarum and Bifidobacterium animalis subsp. lactis. Researchers are excited about this treatment because it targets gut health, which can have a significant impact on overall well-being and is a more natural approach compared to conventional methods. The use of a daily probiotic offers a promising alternative that could support health without the side effects often associated with other treatments.

What evidence suggests that this probiotic treatment could be effective for women's health?

Research shows that probiotics can benefit women's health. Some studies found that certain probiotics improved vaginal health by 50% and significantly reduced inflammation. Participants also reported feeling better overall. In this trial, participants will receive either the Progressive Perfect Probiotic or a placebo. The Progressive Perfect Probiotic includes several strains that might offer these benefits. Although direct evidence about this probiotic's effects on brain function or menstrual cycles is limited, its ingredients suggest potential benefits based on existing research.678910

Are You a Good Fit for This Trial?

This trial is for women interested in exploring how probiotics might affect brain flexibility and health during their menstrual cycle. Participants should be generally healthy, with a regular menstrual cycle, not currently using probiotics or antibiotics, and without gastrointestinal issues.

Inclusion Criteria

I am a right-handed woman, aged 18-35, with a regular menstrual cycle of 26-30 days.

Exclusion Criteria

Contradictions to TMS
I use birth control pills or other hormone-based contraceptives.
Contradictions to probiotic

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either a real probiotic or placebo probiotic for 28 days, with assessments conducted before and after each intervention.

28 days
4 visits (in-person)

Washout

A 28-day washout period between interventions to ensure no carryover effects.

28 days

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Progressive Perfect Probiotic
Trial Overview The study tests if the 'Progressive Perfect Probiotic' can enhance brain adaptability more effectively than a placebo (a substance with no active therapeutic effect). It also examines whether these effects vary at different stages of the menstrual cycle.
How Is the Trial Designed?
2Treatment groups
Active Control
Placebo Group
Group I: Active: ProbioticActive Control1 Intervention
Group II: Placebo ProbioticPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

McMaster University

Lead Sponsor

Trials
936
Recruited
2,630,000+

Citations

Perfect Probiotic Women's Support 30 BillionEach capsule delivers 30 billion active cells to support intestinal health and is enhanced with cranberry extract to help prevent recurrent UTIs in women.
Outcome-Specific Efficacy of Different Probiotic Strains and ...Three probiotic strains and two mixtures were effective in alleviating abdominal bloating. Four probiotic strains and a mixture were ...
Expert Opinion on the Use of Probiotics in General ...Results showed a 50% improvement in the Vaginal Health Index score and significant reductions in inflammatory cytokines: IL-6 (87.8%), IL-1β ( ...
The Impact of Probiotics on Well-being in WomenIn previous studies with healthy adults receiving the Lab4P probiotic the outcomes indicated an overall improvement in general well-being and these findings ...
Effects of daily probiotic supplementation with ...Conclusion: In conclusion, the consumption of L. acidophilus probiotics daily for 12 weeks among postmenopausal women does not affect the profile of BMD, but it ...
Perfect Probiotic Women's Support 30 BillionThis probiotic supports women's digestive and urinary health, with 30 billion CFUs from 10 strains, cranberry extract, and is vegan and shelf-stable.
Progressive Perfect Probiotic for Women with 30 Billion ...Progressive Perfect Probiotic Women's Support delivers 30 billion live cultures plus a high potency cranberry extract in a convenient one per day formula to ...
60 Billion Cfu Per Capsule Extra Strength Perfect ProbioticIf you have food sensitivities or allergies, you should always read the actual product packaging to ensure safety of the product for your situation. Please do ...
Risk and Safety of Probiotics - PMC - PubMed CentralProbiotics have been used safely for years. Safety outcomes are inconsistently reported in published clinical trials.
30 V Perfect Probiotic Women's Support 50 Billion30 V Perfect Probiotic Women's Support 50 Billion - Progressive ; Approx. $42.75 ; Breathe easy. Free returns. ; Popular item. 2 have already sold. ; 女性專門益生菌 ...
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