Physical Activity Coaching for Ataxia

(EngageAtaxia Trial)

Overseen By Chelsea E Macpherson, PT, DPT, NCS

Age: 18+

Sex: Any

Trial Phase: Phase 1

Sponsor: Teachers College, Columbia University

Disqualifiers: Stroke, Cardiac, Pulmonary, Metabolic, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

30 Participants Needed

Trial Summary

What is the purpose of this trial?

Engage-Ataxia will implement a physical activity coaching program for people with cerebellar ataxia at Teachers College, Columbia University. This program expands upon the current Engage program for people with Parkinson's disease (Engage-PD), an exercise coaching program for people with early stage Parkinson's disease to target individuals with early stage cerebellar ataxia. Engage-Ataxia will utilize a physical or occupational therapist to provide up to five one-on-one coaching sessions for individuals newly diagnosed with cerebellar ataxia. Therapists will work with participants to provide individualized structured support to facilitate and optimize exercise uptake as one part of comprehensive disease management. Participants will undertake two assessments three months apart, and will receive coaching interventions via Zoom healthcare platform. The primary objective of this program is to increase physical activity and exercise engagement in individuals with early stage cerebellar ataxia. This feasibility study will provide preliminary data and insight into the benefits of a remote coaching intervention for people with cerebellar ataxia.

Eligibility Criteria

This trial is for individuals with early-stage cerebellar ataxia who can walk indoors and outdoors without help or devices. They should have a SARA score of 8-25, indicating mild to moderate disease, and must be cleared medically to exercise.

Inclusion Criteria

Medical clearance to exercise

My ataxia is in the mild to moderate stage, with a SARA score between 8-25.

I have been cleared by my doctor to participate in physical activities.

Exclusion Criteria

I have a condition that could affect my ability to exercise.

Currently do moderate-vigorous exercise 5 days a week or more

I have a neurological condition like a stroke.

Treatment Details

Interventions

• Physical activity coaching

Trial Overview The study tests a physical activity coaching program delivered via Zoom by therapists. Participants will receive up to five one-on-one sessions aimed at increasing their physical activity as part of managing their condition.

Participant Groups

Group I: Physical Activity Coaching Experimental Treatment 1 Intervention

Participants will receive up to 5 individualized coaching sessions delivered via telehealth to facilitate and optimize exercise uptake. The therapist will facilitate discussion on specific and measurable goals, and will provide options for tracking their progress, such as written or web-based exercise logs or an activity monitor. The recommended exercises will be individualized to each participant but will primarily focus on increasing general physical activity (e.g. steps per day) as well as engagement in moderate intensity aerobic exercise a minimum of three times per week. Balance and strengthening exercises will also be recommended as appropriate.

Who Is Running the Clinical Trial?

Teachers College, Columbia University

Lead Sponsor

Trials

27

Recruited

6,100+