LASIK vs SMILE Eye Surgery for Vision Correction
What You Need to Know Before You Apply
What is the purpose of this trial?
This study evaluates differences in postoperative visual outcomes between patients receiving Topography-Guided LASIK in one eye and Small Incision Lenticule Extraction in the other eye.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, contact lens wearers must stop using hard or gas permeable lenses for at least 4 weeks and soft lenses for at least 5 days before the preoperative screening.
Is LASIK or SMILE eye surgery safe for vision correction?
Both LASIK and SMILE are generally considered safe for vision correction, with SMILE showing high safety and stable outcomes in long-term studies. SMILE may have fewer issues with dry eyes post-surgery and is preferred for those who play contact sports, but it can have complications like suction loss and incision tears, which are manageable without loss of vision.12345
How does SMILE eye surgery differ from other vision correction treatments?
SMILE (Small Incision Lenticule Extraction) is unique because it is a minimally invasive procedure that uses a single laser to correct vision, unlike LASIK which involves creating a flap in the cornea. SMILE is performed through a small incision, which may result in less trauma to the eye and potentially fewer complications like dry eye compared to LASIK.678910
What data supports the effectiveness of LASIK and SMILE eye surgery for vision correction?
Research shows that both SMILE and LASIK are effective for correcting vision problems like myopia (nearsightedness) and astigmatism (blurred vision due to an irregularly shaped cornea). Studies comparing the two treatments indicate that they have similar visual and refractive outcomes, meaning they both improve vision effectively.78101112
Who Is on the Research Team?
Majid Moshirfar, MD
Principal Investigator
Hoopes Vision
Are You a Good Fit for This Trial?
This trial is for people aged 22-50 with near-sightedness or astigmatism, having a stable prescription that hasn't changed much in the last year. They should not have had previous eye surgeries, significant dry eyes, keratoconus, or certain other eye conditions. Pregnant women and those with uncontrolled diabetes or autoimmune diseases are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo refractive correction surgery with either Topography-Guided LASIK or Small Incision Lenticule Extraction
Postoperative Care
Participants receive postoperative care instructions and medications following standard of care practices
Follow-up
Participants are monitored for visual outcomes and safety at 1-day, 1-week, 1-month, 3-month, and 12-month visits
What Are the Treatments Tested in This Trial?
Interventions
- Small Incision Lenticule Extraction Surgery
- Topography Guided LASIK Surgery
Find a Clinic Near You
Who Is Running the Clinical Trial?
Hoopes Vision
Lead Sponsor
Alcon Research
Industry Sponsor
Raquel C. Bono
Alcon Research
Chief Medical Officer since 2022
MD from Harvard Medical School
David Endicott
Alcon Research
Chief Executive Officer since 2018
MBA from University of Southern California