Dr. Wenli GaO
Claim this profileDanbury Hospital
Area of expertise
Breast Cancer
Wenli GaO has run 4 trials for Breast Cancer. Some of their research focus areas include:
Breast Cancer
Wenli GaO has run 4 trials for Breast cancer. Some of their research focus areas include:
Affiliated Hospitals
Danbury Hospital
Clinical Trials Wenli GaO is currently running
Herceptin Hylecta or Phesgo + Chemotherapy
for Uterine Cancer
This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops tumor cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial cancer.
Recruiting
2 awards
Phase 3
Pembrolizumab
for Triple-Negative Breast Cancer
The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial may help researchers determine if observation will result in the same risk of cancer coming back as pembrolizumab after surgery in triple-negative breast cancer patients who achieve pathologic complete response after preoperative chemotherapy with pembrolizumab.
Recruiting
2 awards
Phase 3
19 criteria
More about Wenli GaO
Clinical Trial Related
7 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Wenli GaO has experience with
- Carboplatin
- Atezolizumab
- Trastuzumab
- Paclitaxel
- Pertuzumab
- Pembrolizumab
Breakdown of trials Wenli GaO has run
Breast Cancer
Breast cancer
Pancreatic Cancer
HER2-Positive Breast Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Wenli GaO specialize in?
Wenli GaO focuses on Breast Cancer and Breast cancer. In particular, much of their work with Breast Cancer has involved HER2 positive patients, or patients who are ER negative.
Is Wenli GaO currently recruiting for clinical trials?
Yes, Wenli GaO is currently recruiting for 2 clinical trials in Danbury Connecticut. If you're interested in participating, you should apply.
Are there any treatments that Wenli GaO has studied deeply?
Yes, Wenli GaO has studied treatments such as Carboplatin, Atezolizumab, Trastuzumab.
What is the best way to schedule an appointment with Wenli GaO?
Apply for one of the trials that Wenli GaO is conducting.
What is the office address of Wenli GaO?
The office of Wenli GaO is located at: Danbury Hospital, Danbury, Connecticut 06810 United States. This is the address for their practice at the Danbury Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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