Dr. Vandana Abramson, M.D.
Claim this profileVanderbilt University/Ingram Cancer Center
Expert in Breast Cancer
Studies Breast cancer
14 reported clinical trials
31 drugs studied
Area of expertise
1Breast Cancer
Global LeaderHER2 positive
ER negative
HER2 negative
2Breast Cancer
HER2 positive
ER negative
Stage IV
Affiliated Hospitals
Clinical Trials Vandana Abramson, M.D. is currently running
ZEN-3694 + Pembrolizumab + Chemotherapy
for Breast Cancer
This phase Ib trial tests the safety and tolerability of ZEN003694 in combination with an immunotherapy drug called pembrolizumab and the usual chemotherapy approach with nab-paclitaxel for the treatment of patients with triple negative-negative breast cancer that has spread to other parts of the body (advanced). Paclitaxel is in a class of medications called antimicrotubule agents. It stops cancer cells from growing and dividing and may kill them. Nab-paclitaxel is an albumin-stabilized nanoparticle formulation of paclitaxel which may have fewer side effects and work better than other forms of paclitaxel. Immunotherapy with monoclonal antibodies, such as pembrolizumab may help the body's immune system attach the cancer and may interfere with the ability of tumor cells to grow and spread. ZEN003694 is an inhibitor of a family of proteins called the bromodomain and extra-terminal (BET). It may prevent the growth of tumor cells that over produce BET protein. Combination therapy with ZEN003694 pembrolizumab immunotherapy and nab-paclitaxel chemotherapy may help shrink or stabilize cancer for longer than chemotherapy alone.
Recruiting1 award Phase 1
Endoxifen
for Breast Cancer
This trial is testing (Z)-endoxifen, a drug that blocks estrogen, in pre-menopausal women with a specific type of breast cancer. The study aims to see if this drug can slow down cancer growth by measuring a marker called Ki-67. Participants will take the drug daily for several months before surgery.
Recruiting1 award Phase 27 criteria
More about Vandana Abramson, M.D.
Clinical Trial Related8 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments Vandana Abramson, M.D. has experience with
- Trastuzumab
- Pembrolizumab
- Sacituzumab Govitecan
- Avelumab
- Atezolizumab
- Pertuzumab
Breakdown of trials Vandana Abramson, M.D. has run
Breast Cancer
Breast cancer
Parotid Gland Cancer
PALB2 Mutation
BRCA2 Mutation
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