Dr. Timothy J. Panella
Claim this profileUniversity of Tennessee - Knoxville
Studies Breast Cancer
Studies Skin Cancer
9 reported clinical trials
19 drugs studied
Area of expertise
1Breast Cancer
HER2 positive
ER positive
PR negative
2Skin Cancer
Stage IV
Stage III
Stage I
Affiliated Hospitals
Clinical Trials Timothy J. Panella is currently running
Imlunestrant
for Early Breast Cancer
This trial is testing a new medication called imlunestrant to see if it works better than standard hormone treatments for certain breast cancer patients. The study focuses on patients with early-stage breast cancer that is estrogen receptor positive and HER2 negative, who have already been on hormone therapy for a period of time and are at high risk of their cancer returning. Imlunestrant works by blocking estrogen from helping cancer cells grow.
Recruiting2 awards Phase 36 criteria
T-DM1 + Tucatinib
for Breast Cancer
This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as HER2 receptors, and delivers DM1 to kill them. Tucatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving T-DM1 and tucatinib may work better in preventing breast cancer from relapsing in patients with HER2 positive breast cancer compared to T-DM1 alone.
Recruiting1 award Phase 313 criteria
More about Timothy J. Panella
Clinical Trial Related4 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Timothy J. Panella has experience with
- Pembrolizumab
- PDS0101
- Abemaciclib
- Anastrozole
- Imlunestrant
- Tamoxifen
Breakdown of trials Timothy J. Panella has run
Breast Cancer
Skin Cancer
Parotid Gland Cancer
Squamous Cell Carcinoma
Oropharyngeal Carcinoma
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