Tian Zhang, M.D. - Faculty Profile - UT ...

Dr. Tian Zhang, MD

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University of Texas Southwestern Medical Center at Dallas

Studies Renal Cell Carcinoma
Studies Kidney Cancer
11 reported clinical trials
14 drugs studied

Area of expertise

1Renal Cell Carcinoma
Tian Zhang, MD has run 3 trials for Renal Cell Carcinoma. Some of their research focus areas include:
Stage IV
Stage III
2Kidney Cancer
Tian Zhang, MD has run 3 trials for Kidney Cancer. Some of their research focus areas include:
Stage IV
Stage III

Affiliated Hospitals

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University Of Texas Southwestern Medical Center
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University Of Texas Southwestern Medical Center At Dallas

Clinical Trials Tian Zhang, MD is currently running

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Registry

for Advanced Prostate Cancer

Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingdom (UK), and the United States (US). Target accrual number and number of participating sites are subject to change based on accrual, funding, and interest in participation by other international sites. This cohort study will facilitate a better understanding of the variation in care and treatment of advanced prostate cancer across countries and across academia and community based practices. Detailed data will be collected from patients at study enrollment and then during follow-up, for a minimum of five years. Patients will be followed prospectively for overall survival, clinically significant adverse events, comorbidities, changes in cancer treatments, and PROMs. PROMs questionnaires will be collected at enrollment and every three months thereafter. Physician Questionnaires will be collected from all participating sites at patient enrollment, time of first change in treatment and/or one year follow-up, at each subsequent change of treatment, and discontinuation of treatment. As such, this registry will help identify the treatment sequences or combinations that optimize overall survival and PROMs for men with mHSPC and M0/M1 CRPC. By collecting blood at enrollment, time of first change in treatment and/or one year follow-up (plasma, cell free DNA, buffy coat / RNA), this registry will further identify and validate molecular phenotypes of disease that predict response and resistance to specific therapeutics. Additionally, every effort will be made to collect blood specimen at each subsequent change in treatment due to progression of disease. When feasible, existing tumor tissue may be collected for correlation with described blood based studies. All samples will be used for future research. This cohort study will provide the research community with a unique biorepository to identify biomarkers of treatment response and resistance.
Recruiting1 award N/A5 criteria
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Cabozantinib + Nivolumab

for Kidney Cancer

This trial is testing higher doses of cabozantinib or a combination of cabozantinib with nivolumab in patients with advanced kidney cancer who did not respond to previous treatment. Cabozantinib stops cancer growth, while nivolumab helps the immune system fight the cancer. Cabozantinib and nivolumab have been used together to treat advanced renal cell carcinoma, showing benefits in disease control and survival.
Recruiting1 award Phase 2

More about Tian Zhang, MD

Clinical Trial Related1 year of experience running clinical trials · Led 11 trials as a Principal Investigator · 6 Active Clinical Trials
Treatments Tian Zhang, MD has experience with
  • Nivolumab
  • Cabozantinib
  • Enfortumab Vedotin
  • Pembrolizumab
  • Standard Of Care
  • Lutetium Lu 177 Vipivotide Tetraxetan

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