Dr. Thanh H. Dellinger

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City of Hope Medical Center

Studies Uterine Cancer
Studies Ovarian Cancer
3 reported clinical trials
13 drugs studied

Affiliated Hospitals

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City Of Hope Medical Center

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City Of Hope

Clinical Trials Thanh H. Dellinger is currently running

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PIPAC

for Peritoneal Cancer

This phase I trial studies the side effects of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in treating patients with ovarian, uterine, appendiceal, stomach (gastric), or colorectal cancer that has spread to the lining of the abdominal cavity (peritoneal carcinomatosis). Chemotherapy drugs, such as cisplatin, doxorubicin, oxaliplatin, leucovorin, fluorouracil, mitomycin, and irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. PIPAC is a minimally invasive procedure that involves the administration of intraperitoneal chemotherapy. The study device consists of a nebulizer (a device that turns liquids into a fine mist), which is connected to a high-pressure injector, and inserted into the abdomen (part of the body that contains the digestive organs) during a laparoscopic procedure (a surgery using small incisions to introduce air and to insert a camera and other instruments in the abdominal cavity for diagnosis and/or to perform routine surgical procedures). Pressurization of the liquid chemotherapy through the study device results in aerosolization (a fine mist or spray) of the chemotherapy intra-abdominally (into the abdomen). Giving chemotherapy through PIPAC may reduce the amount of chemotherapy needed to achieve acceptable drug concentration, and therefore potentially reduces side effects and toxicities.

Recruiting

1 award

Phase 1

18 criteria

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HIPEC with Surgery

for Ovarian Cancer

This trial tests if combining surgery with heated chemotherapy improves outcomes for patients with stage III ovarian cancer compared to surgery alone. Heated chemotherapy has shown improved disease-free and overall survival in patients with stage III ovarian cancer when combined with surgery to remove as much of the tumor as possible.

Recruiting

2 awards

Phase 3

2 criteria

More about Thanh H. Dellinger

Clinical Trial Related

7 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Thanh H. Dellinger has experience with

  • Cisplatin
  • Megestrol Acetate
  • Pterostilbene
  • Biopsy
  • Doxorubicin
  • Fluorouracil

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