Dr. Steven M. Duffy, MD | East Syracuse ...

Dr. Steven M. Duffy

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Hematology Oncology Associates of Central New York-East Syracuse

Studies Breast Cancer
Studies Lung Cancer
19 reported clinical trials
38 drugs studied

Area of expertise

1Breast Cancer
Steven M. Duffy has run 6 trials for Breast Cancer. Some of their research focus areas include:
ER positive
HER2 positive
ER negative
2Lung Cancer
Steven M. Duffy has run 5 trials for Lung Cancer. Some of their research focus areas include:
Stage III
Stage IV
Stage II

Affiliated Hospitals

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Hematology Oncology Associates Of Central New York-East Syracuse
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Hematology Oncology Associates Of Central New York-Onondaga Hill

Clinical Trials Steven M. Duffy is currently running

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Combination Therapy

for Multiple Myeloma

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Daratumumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. Anti-inflammatory drugs, such as dexamethasone lower the body's immune response and are used with other drugs in the treatment of some types of cancer. Adding bortezomib to daratumumab, lenalidomide, and dexamethasone may be more effective in shrinking the cancer or preventing it from returning, compared to continuing on daratumumab, lenalidomide, and dexamethasone.
Recruiting2 awards Phase 332 criteria
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Zanubrutinib

for Mantle Cell Lymphoma

This phase III trial tests whether continuous or intermittent zanubrutinib after achieving a complete remission (CR) with rituximab works in older adult patients with mantle cell lymphoma (MCL) who have not received treatment in the past (previously untreated). Rituximab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. Zanubrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. When zanubrutinib is used in MCL, the current standard of care is to continue administering the drug indefinitely until disease progression. This continuous treatment comes with clinical as well as financial toxicity, which could be especially detrimental in older patients. For patients who achieve a CR after initial zanubrutinib plus rituximab therapy, it may be safe and equally effective to stop treatment and restart zanubrutinib upon disease progression rather than continuing indefinitely in previously untreated older adult patients with MCL.
Recruiting2 awards Phase 310 criteria

More about Steven M. Duffy

Clinical Trial Related5 years of experience running clinical trials · Led 19 trials as a Principal Investigator · 10 Active Clinical Trials
Treatments Steven M. Duffy has experience with
  • Biospecimen Collection
  • Pembrolizumab
  • Carboplatin
  • Tamoxifen
  • Atezolizumab
  • Durvalumab

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