Dr. Sonal Paul

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Sinai Hospital of Baltimore

Studies Rectal Cancer
Studies Colon Cancer
4 reported clinical trials
9 drugs studied

Area of expertise

1

Rectal Cancer

Sonal Paul has run 2 trials for Rectal Cancer. Some of their research focus areas include:

Stage III
Stage II
MSH2 negative
2

Colon Cancer

Sonal Paul has run 1 trial for Colon Cancer. Some of their research focus areas include:

Stage III
MSS positive
MMR positive

Affiliated Hospitals

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Sinai Hospital Of Baltimore

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William E Kahlert Regional Cancer Center/Sinai Hospital

Clinical Trials Sonal Paul is currently running

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Recruiting

2 awards

Phase 3

2 criteria

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Chemotherapy Tailored by ctDNA Status

for Colon Cancer

This trial tests if a blood test for cancer DNA can help decide if colon cancer patients need more treatment after surgery. The test looks for cancer DNA in the blood to predict if the cancer might come back and to guide further treatment.

Recruiting

1 award

Phase 2 & 3

More about Sonal Paul

Clinical Trial Related

3 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Sonal Paul has experience with

  • MFOLFIRINOX
  • Irinotecan
  • Oxaliplatin
  • CAPOX
  • MFOLFOX6
  • Signatera Test

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