Scott T. Tagawa, M.D., MS, FACP, FASCO ...

Dr. Scott Tagawa, MD

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Weill Cornell Medical College

Expert in Prostate Cancer
Studies Renal Cell Carcinoma
14 reported clinical trials
32 drugs studied

Area of expertise

1

Prostate Cancer

Global Leader

Scott Tagawa, MD has run 13 trials for Prostate Cancer. Some of their research focus areas include:

Stage IV
2

Renal Cell Carcinoma

Scott Tagawa, MD has run 1 trial for Renal Cell Carcinoma. Some of their research focus areas include:

Stage IV
Stage III
TFE-3/B translocation positive

Affiliated Hospitals

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Weill Cornell Medical College

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NYP/Weill Cornell Medical Center

Clinical Trials Scott Tagawa, MD is currently running

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Registry

for Advanced Prostate Cancer

Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingdom (UK), and the United States (US). Target accrual number and number of participating sites are subject to change based on accrual, funding, and interest in participation by other international sites. This cohort study will facilitate a better understanding of the variation in care and treatment of advanced prostate cancer across countries and across academia and community based practices. Detailed data will be collected from patients at study enrollment and then during follow-up, for a minimum of five years. Patients will be followed prospectively for overall survival, clinically significant adverse events, comorbidities, changes in cancer treatments, and PROMs. PROMs questionnaires will be collected at enrollment and every three months thereafter. Physician Questionnaires will be collected from all participating sites at patient enrollment, time of first change in treatment and/or one year follow-up, at each subsequent change of treatment, and discontinuation of treatment. As such, this registry will help identify the treatment sequences or combinations that optimize overall survival and PROMs for men with mHSPC and M0/M1 CRPC. By collecting blood at enrollment, time of first change in treatment and/or one year follow-up (plasma, cell free DNA, buffy coat / RNA), this registry will further identify and validate molecular phenotypes of disease that predict response and resistance to specific therapeutics. Additionally, every effort will be made to collect blood specimen at each subsequent change in treatment due to progression of disease. When feasible, existing tumor tissue may be collected for correlation with described blood based studies. All samples will be used for future research. This cohort study will provide the research community with a unique biorepository to identify biomarkers of treatment response and resistance.

Recruiting

1 award

N/A

5 criteria

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Pembrolizumab + AR Inhibitors

for Prostate Cancer

This is a phase I/II study investigating the combination of 225Ac-J591 (a drug that can deliver radiation to prostate cancer cells) with pembrolizumab (immunotherapy, a drug that increases the immune system's ability to destroy cancer cells). This study will assess whether 225Ac-J591 + pembrolizumab + androgen receptor inhibitor (ARI) is more effective against prostate cancer than pembrolizumab + ARI alone.

Recruiting

2 awards

Phase 1 & 2

9 criteria

More about Scott Tagawa, MD

Clinical Trial Related

4 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Scott Tagawa, MD has experience with

  • 225Ac-J591
  • Pembrolizumab
  • Abiraterone Acetate
  • Apalutamide
  • Prednisone
  • ARX517

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