Satiro De Oliveira, MD - Pediatric ...

Dr. Satiro De Oliveira, MD

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Mattel Children's Hospital UCLA

Studies Brain Tumor
Studies Neuroblastoma
18 reported clinical trials
58 drugs studied

About Satiro De Oliveira, MD

Education:

  • Graduated with an MD from Faculdade de Medicina da Universidade de São Paulo, Brazil, in 1995.

Experience:

  • Completed an Internal Medicine Internship and Pediatrics Residency at Hospital das Clinicas da FMUSP, Brazil.
  • Undertook a Pediatrics Residency at Woodhull Medical & Mental Health Center, New York, in 2007.
  • Completed Pediatric Hematology-Oncology Fellowships at Boldrini Children's Center, Brazil, and Children's Hospital of Los Angeles.

Area of expertise

1

Brain Tumor

Satiro De Oliveira, MD has run 6 trials for Brain Tumor. Some of their research focus areas include:

Stage IV
Stage I
Stage II
2

Neuroblastoma

Satiro De Oliveira, MD has run 6 trials for Neuroblastoma. Some of their research focus areas include:

MYC positive
Stage IV
Stage I

Affiliated Hospitals

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Mattel Children's Hospital - UCLA

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University Of California Los Angeles (UCLA)

Clinical Trials Satiro De Oliveira, MD is currently running

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Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.

Recruiting

2 awards

Phase 3

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Inotuzumab Ozogamicin

for Acute Lymphoblastic Leukemia

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.

Recruiting

2 awards

Phase 3

More about Satiro De Oliveira, MD

Clinical Trial Related

6 years of experience running clinical trials · Led 18 trials as a Principal Investigator · 8 Active Clinical Trials

Treatments Satiro De Oliveira, MD has experience with

  • Cyclophosphamide
  • Doxorubicin Hydrochloride
  • Radiation Therapy
  • Tipifarnib
  • Selpercatinib
  • Cisplatin

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