Dr. Sarah Holstein
Claim this profileUniversity of Nebraska Medical Center
Studies Multiple Myeloma
Studies Immune Dysfunction
9 reported clinical trials
17 drugs studied
Area of expertise
1Multiple Myeloma
Stage III
Stage IV
2Immune Dysfunction
Affiliated Hospitals
Clinical Trials Sarah Holstein is currently running
Iberdomide
for Multiple Myeloma
This phase II trial compares iberdomide maintenance therapy to disease monitoring for improving survival in patients who have received idecabtagene vicleucel (a type of chimeric antigen receptor T-cell \[CAR-T\] therapy) for multiple myeloma. The usual approach after treatment with idecabtagene vicleucel is to monitor the multiple myeloma without giving myeloma medications. There is currently no medication approved specifically for use after idecabtagene vicleucel treatment. Upon administration, iberdomide modifies the immune system and activates immune cells called T-cells, which could enhance the effectiveness of idecabtagene vicleucel. Iberdomide may keep multiple myeloma under control for longer than the usual approach (disease monitoring) after idecabtagene vicleucel, and may help multiple myeloma patients live longer.
Recruiting1 award Phase 210 criteria
Lenalidomide + Dexamethasone +/- Daratumumab
for Multiple Myeloma
This phase III trial studies how well lenalidomide and dexamethasone works with or without daratumumab in treating patients with high-risk smoldering myeloma. Drugs used in chemotherapy, such as lenalidomide and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as daratumumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Giving lenalidomide and dexamethasone with daratumumab may work better in treating patients with smoldering myeloma.
Recruiting2 awards Phase 312 criteria
More about Sarah Holstein
Clinical Trial Related1 year of experience running clinical trials · Led 9 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Sarah Holstein has experience with
- Dexamethasone
- Daratumumab
- Lenalidomide
- Iberdomide
- Ixazomib
- CYNK-001
Breakdown of trials Sarah Holstein has run
Multiple Myeloma
Immune Dysfunction
Immunoproliferative Disorders
Sensory System Agents
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Sarah Holstein specialize in?
Sarah Holstein focuses on Multiple Myeloma and Immune Dysfunction. In particular, much of their work with Multiple Myeloma has involved Stage III patients, or patients who are Stage IV.
Is Sarah Holstein currently recruiting for clinical trials?
Yes, Sarah Holstein is currently recruiting for 4 clinical trials in Omaha Nebraska. If you're interested in participating, you should apply.
Are there any treatments that Sarah Holstein has studied deeply?
Yes, Sarah Holstein has studied treatments such as Dexamethasone, Daratumumab, Lenalidomide.
What is the best way to schedule an appointment with Sarah Holstein?
Apply for one of the trials that Sarah Holstein is conducting.
What is the office address of Sarah Holstein?
The office of Sarah Holstein is located at: University of Nebraska Medical Center, Omaha, Nebraska 68198 United States. This is the address for their practice at the University of Nebraska Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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