Sant Chawla MD - SARC Clinical Trialist ...

Dr. Sant P Chawla, MD

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Sarcoma Oncology Center

Expert in Soft Tissue Sarcoma
Studies Solid Tumors
42 reported clinical trials
59 drugs studied

About Sant P Chawla, MD

Education:

  • Earned a Medical Degree from All India Institute of Medical Sciences, New Delhi, India.

Experience:

  • Completed Residency in Internal Medicine at All India Institute of Medical Sciences, New Delhi.
  • Underwent Specialty training in Medical Oncology at Auckland Hospital, Auckland, New Zealand.
  • Achieved Fellowships in Medical Oncology at Fellow Royal Australasian College of Physicians (F.R.A.C.P.) and in Oncology at the University of Texas MD Anderson Cancer Center.
  • Serves as Director of the Sarcoma Oncology Center in Santa Monica, CA, and holds clinical faculty positions at UCLA, USC, John Wayne Cancer Institute at St. John’s Hospital, and Cedars Sinai Comprehensive Cancer Center.
  • Recognized for conducting over 100 clinical trials for cancer drugs and groundbreaking research in sarcoma oncology.

Area of expertise

1Soft Tissue Sarcoma
Global Leader
Sant P Chawla, MD has run 18 trials for Soft Tissue Sarcoma. Some of their research focus areas include:
Stage IV
Stage III
HCV
2Solid Tumors
Sant P Chawla, MD has run 9 trials for Solid Tumors. Some of their research focus areas include:
Stage IV
Stage III
KRAS positive

Affiliated Hospitals

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Sarcoma Oncology Center
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Sarcoma Oncology Research Center

Clinical Trials Sant P Chawla, MD is currently running

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Chemotherapy + Immunotherapy

for Advanced Sarcoma

This trial uses a combination of chemotherapy and immunotherapy to treat patients with advanced sarcoma. The chemotherapy attacks the cancer directly, while the immunotherapy boosts the body's natural defenses to help fight the cancer.
Recruiting1 award Phase 212 criteria
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Bria-OTS Immunotherapy

for Breast Cancer

This is an open-label Phase 1/2a study. Once the safety of the BC1 cell line alone has been demonstrated in Phase 1, in Phase 2, patients will be treated with the Bria-OTS regimen (see below) and a clinically available check point inhibitor (CPI). During the monotherapy phase of Phase 1, one patient will be treated intradermally every 2 weeks for 6 weeks (4 doses) with an initial dose of the BC1 cell line. If this dose is tolerated, the next patient will receive an increased dose of BC1. If once again tolerated, the third patient will receive a further dose increase of the BC1. Once at least 3 patients have been safely treated with the BC1 cell line, with no dose-limiting toxicity (DLT), the combinational phase of the study will commence. Following the monotherapy phase, patients will be treated with BC1 and the Bria-OTS regimen (see below) every 3 weeks, plus a CPI at the FDA approved labelled dose and schedule. There will be at least a 2-week spacing between enrollment of each of the first three subjects in the study in order to assess for any early unanticipated risk(s). During the Phase 1 combination and Phase 2 expansion phases, all patients will be treated with BC1 cells as part of the Bria-OTS regimen, which includes cyclophosphamide 300 mg/m2 2-3 days prior to BC1 cell inoculation, and peginterferon alpha-2a administered on the same day, following BC1 cell inoculation.
Recruiting1 award Phase 1 & 27 criteria

More about Sant P Chawla, MD

Clinical Trial Related3 years of experience running clinical trials · Led 42 trials as a Principal Investigator · 10 Active Clinical Trials
Treatments Sant P Chawla, MD has experience with
  • Nivolumab
  • Doxorubicin
  • Trabectedin
  • Gemcitabine
  • Placebo
  • L19TNF

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