Dr. Samuel Klein, MD
Claim this profileWashington University School of Medicine
Studies Obesity
Studies Insulin Resistance
8 reported clinical trials
13 drugs studied
Affiliated Hospitals
Clinical Trials Samuel Klein, MD is currently running
Weight Loss Strategies
for Obesity
The purpose of this study is to compare the metabolic responses to low-carbohydrate and standard-carbohydrate meals in African Americans and non-Hispanic White adults with obesity and the effect of weight loss induced by low-calorie diet (LCD) or Roux-en-Y gastric bypass (RYGB) on the metabolic responses to low-carbohydrate and standard meals. Participants will consume: 1) a standard-carbohydrate meal (\~49 g glucose) and 2) a low-carbohydrate (\~3.4 g glucose) meal on separate study visits performed in a randomized order. We will evaluate the meals' effect before and after \~16-18% weight loss on postprandial i) insulin kinetics, ii) glucose kinetics iii) β-cell function; iv) plasma triglyceride and non-esterified fatty acid concentrations; v) plasma hormone concentrations; vi) plasma cytokine concentrations; vi) plasma metabolomics; and vii) adipose tissue transcriptomics.
Recruiting1 award N/A2 criteria
Ketogenic Diet
for Type 1 Diabetes
Despite strong evidence that tight control of blood sugar reduces the risk of diabetes complications, most people with type 1 diabetes do not achieve recommended blood sugar targets. This randomized controlled trial will test whether a very-low- carbohydrate ketogenic diet can effectively and safely improve blood sugar control in adults with type 1 diabetes.
Recruiting1 award N/A3 criteria
More about Samuel Klein, MD
Clinical Trial Related8 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Samuel Klein, MD has experience with
- Mediterranean Diet
- Roux-en-Y Gastric Bypass
- Low-calorie Diet
- Ketogenic Diet
- Low-fat Diet
- Low-carbohydrate, Ketogenic Diet
Breakdown of trials Samuel Klein, MD has run
Obesity
Weight Loss
Type 2 Diabetes
Hypoglycemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Samuel Klein, MD specialize in?
Samuel Klein, MD focuses on Obesity and Insulin Resistance. In particular, much of their work with Obesity has involved treating patients, or patients who are undergoing treatment.
Is Samuel Klein, MD currently recruiting for clinical trials?
Yes, Samuel Klein, MD is currently recruiting for 2 clinical trials in Saint Louis Missouri. If you're interested in participating, you should apply.
Are there any treatments that Samuel Klein, MD has studied deeply?
Yes, Samuel Klein, MD has studied treatments such as Mediterranean diet, Roux-en-Y Gastric Bypass, Low-calorie diet.
What is the best way to schedule an appointment with Samuel Klein, MD?
Apply for one of the trials that Samuel Klein, MD is conducting.
What is the office address of Samuel Klein, MD?
The office of Samuel Klein, MD is located at: Washington University School of Medicine, Saint Louis, Missouri 63110 United States. This is the address for their practice at the Washington University School of Medicine.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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