Dr. Saima Sharif, MD
Claim this profileUniversity of Iowa/Holden Comprehensive Cancer Center
Studies Colon Cancer
Studies Colorectal Cancer
10 reported clinical trials
25 drugs studied
Area of expertise
1Colon Cancer
Stage IV
Stage III
Stage II
2Colorectal Cancer
Stage IV
Stage III
Stage II
Affiliated Hospitals
Clinical Trials Saima Sharif, MD is currently running
Chemotherapy + Immunotherapy
for Esophageal and Gastric Cancer
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
Dostarlimab
for Colon Cancer
This trial is testing the immunotherapy drug dostarlimab in patients with Stage II and III colon cancer. The goal is to see if the drug can shrink the tumors enough to avoid surgery. Dostarlimab helps the immune system attack the cancer cells.
Recruiting2 awards Phase 2
More about Saima Sharif, MD
Clinical Trial Related2 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Saima Sharif, MD has experience with
- Dostarlimab
- Fluorouracil
- Leucovorin
- Irinotecan
- Leucovorin Calcium
- Oxaliplatin
Breakdown of trials Saima Sharif, MD has run
Colon Cancer
Colorectal Cancer
Stomach Cancer
Uterine Tumors
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Saima Sharif, MD specialize in?
Saima Sharif, MD focuses on Colon Cancer and Colorectal Cancer. In particular, much of their work with Colon Cancer has involved Stage IV patients, or patients who are Stage III.
Is Saima Sharif, MD currently recruiting for clinical trials?
Yes, Saima Sharif, MD is currently recruiting for 4 clinical trials in Iowa City Iowa. If you're interested in participating, you should apply.
Are there any treatments that Saima Sharif, MD has studied deeply?
Yes, Saima Sharif, MD has studied treatments such as Dostarlimab, Fluorouracil, Leucovorin.
What is the best way to schedule an appointment with Saima Sharif, MD?
Apply for one of the trials that Saima Sharif, MD is conducting.
What is the office address of Saima Sharif, MD?
The office of Saima Sharif, MD is located at: University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa 52242 United States. This is the address for their practice at the University of Iowa/Holden Comprehensive Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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