Rohit Loomba, MD, Named Chief of the ...

Dr. Rohit Loomba

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University of California, San Diego

Studies Nonalcoholic Steatohepatitis
Studies Non-alcoholic Fatty Liver Disease
12 reported clinical trials
12 drugs studied

Area of expertise

1Nonalcoholic Steatohepatitis
Rohit Loomba has run 9 trials for Nonalcoholic Steatohepatitis. Some of their research focus areas include:
Stage I
Stage II
2Non-alcoholic Fatty Liver Disease
Rohit Loomba has run 9 trials for Non-alcoholic Fatty Liver Disease. Some of their research focus areas include:
Stage I
Stage II

Affiliated Hospitals

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UC San Diego School Of Medicine - Altman Clinical And Translational Research Institute
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NAFLD Research Center - Altman Clinical And Translational Research Institute

Clinical Trials Rohit Loomba is currently running

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Non-alcoholic Fatty Liver Disease

for People with HIV

Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated with fat accumulation that ranges from benign, non-progressive liver fat accumulation to severe liver injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in US adults and the second leading cause for liver transplantation in the US. The natural history of NAFLD in the general population has been well described, with those with non-alcoholic fatty liver (NAFL, or simple steatosis) destined to have rare incidence of hepatic events compared to those with non-alcoholic steatohepatitis (NASH), who are at high risk for future development of cirrhosis, liver cancer and liver failure. The NASH Clinical Research Network (NASH CRN) was established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in 2002, through the mechanism of RFA-DK-01-025, to further the understanding of diagnosis, mechanisms, progression and therapies of NASH. The NASH CRN effort has resulted in numerous seminal studies in the field. However, NASH CRN studies have systematically excluded persons living with HIV (PLWH), as NAFLD in these persons was thought to be different from that in the general population due to HIV, ART, concomitant medications, and co-infections. This has resulted in major knowledge gaps regarding NAFLD in the setting of HIV. This ancillary study of NAFLD and NASH in Adults with HIV (HIV NASH CRN), HNC 001 goal is to examine the prevalence of hepatic steatosis and NAFLD in a large, multicenter, and multiethnic cohort of PLWH (Steatosis in HIV Study)
Recruiting1 award N/A3 criteria
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Nonalcoholic Fatty Liver Disease

for HIV

Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated with fat accumulation that ranges from benign, non-progressive liver fat accumulation to severe liver injury, cirrhosis, and liver failure. The spectrum of NAFLD encompasses simple nonalcoholic steatosis (nonalcoholic fatty liver \[NAFL\]) and nonalcoholic steatohepatitis (NASH) in which there is evidence of hepatocellular injury and/or fibrosis. NAFLD is the most common liver disease in adults and the second leading cause for liver transplantation in the U.S. The natural history of NAFLD in the general population has been well described. The NASH Clinical Research Network (NASH CRN) was established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in 2002 to further the understanding of the diagnosis, mechanisms, progression and therapies of NASH. This effort has resulted in numerous seminal studies in the field. However, NASH CRN studies have systematically excluded persons living with HIV (PLWH) , as NAFLD in PLWH was thought to be different from that in the general population due to HIV infection, antiretroviral therapy (ART), concomitant medications and co-infections. This resulted in major knowledge gaps regarding NAFLD in the setting of HIV infection. Thus, the natural history of NAFLD in PLWH is largely unknown. The goal of this ancillary study of NAFLD and NASH in Adults with HIV (HIV NASH CRN), is to conduct a prospective, observational, multicenter study of NAFLD in PLWH (HIV-associated NAFLD).
Recruiting1 award N/A8 criteria

More about Rohit Loomba

Clinical Trial Related5 years of experience running clinical trials · Led 12 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Rohit Loomba has experience with
  • Placebo
  • Semaglutide
  • BMS-986263
  • Placebo Of HM15211
  • HM15211
  • Tirzepatide

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