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Dr. Roberto Pili, MD

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Indiana University/ Melvin and Bren Simon Cancer Center

Studies Prostate Cancer
Studies Bladder Cancer
7 reported clinical trials
19 drugs studied

Area of expertise

1

Prostate Cancer

Roberto Pili, MD has run 3 trials for Prostate Cancer.

2

Bladder Cancer

Roberto Pili, MD has run 2 trials for Bladder Cancer. Some of their research focus areas include:

Stage IV
Stage III

Affiliated Hospitals

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Indiana University/Melvin And Bren Simon Cancer Center

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University At Buffalo / Great Lakes Cancer Care

Clinical Trials Roberto Pili, MD is currently running

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Immunotherapy + Chemotherapy

for Bladder Cancer

Upon successful screening and registration, enrollment to durvalumab monotherapy (cohort 1) will begin. If DLT criteria outlined in the protocol are exceeded with durvalumab monotherapy (cohort 1), the study will close. Provided the safety of durvalumab monotherapy is established, enrollment to combination regimen cohorts will proceed. Cohorts will simultaneously enroll in parallel to each other with patients assigned to cohorts based on patient slot availability and study site choice of radiation arm participation. Patient assignment to future phase 1 arms would proceed similarly. Within BCG-containing cohorts, treatment will begin at full-dose BCG. If DLT criteria outlined in Section 5.1.4 are exceeded with full-dose BCG, a one level dose reduction of BCG will be implemented. If DLT criteria outlined in Section 5.1.4 are exceeded with reduced-dose BCG, the BCG-containing cohort will not proceed to Phase 2 of the study. Similarly, if DLT criteria outlined in Section 5.1.4 are exceeded within non-BCG containing cohorts, the non-BCG containing cohort will not proceed to phase 2 of the study. Due to the prolonged half-life of antibody therapies, no dose adjustments are planned for durvalumab in any of the cohorts.

Recruiting

1 award

Phase 1 & 2

6 criteria

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Caloric Restriction and Plant-Based Diet

for Cancer

Caloric restriction may alter the response to chemotherapy induced stress response and enhance its antitumor effect. This study intends to use an intermitted caloric restriction protocol with alternate days before the chemotherapy administration to enhance the cytotoxic effect generated by standard treatment of cancer.

Recruiting

1 award

N/A

More about Roberto Pili, MD

Clinical Trial Related

8 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Roberto Pili, MD has experience with

  • Docetaxel
  • Gemcitabine
  • Intermittent Fasting
  • Tremelimumab
  • External Beam Radiotherapy (EBRT)
  • Durvalumab

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