Dr. Robert J. Hayashi
Claim this profileWashington University School of Medicine
Area of expertise
Cancer
Robert J. Hayashi has run 27 trials for Cancer. Some of their research focus areas include:
Solid Tumors
Robert J. Hayashi has run 18 trials for Solid Tumors. Some of their research focus areas include:
Affiliated Hospitals
Washington University School Of Medicine
St. Louis Children's Hospital - Washington University School Of Medicine
Clinical Trials Robert J. Hayashi is currently running
Inotuzumab Ozogamicin
for Acute Lymphoblastic Leukemia
This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting
2 awards
Phase 3
Health Study After Leukemia Treatment
for People With Down Syndrome
This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear of their risk for long-term effects of cancer treatment. By learning more about the factors that may contribute to chronic health conditions and long-term effects after treatment for leukemia in persons with Down syndrome, clinical practice guidelines for survivorship care can be developed to help improve their quality-of-life.
Recruiting
1 award
N/A
10 criteria
More about Robert J. Hayashi
Clinical Trial Related
8 years of experience running clinical trials · Led 58 trials as a Principal Investigator · 17 Active Clinical Trials
Treatments Robert J. Hayashi has experience with
- Nivolumab
- Etoposide
- Vincristine Sulfate
- Doxorubicin Hydrochloride
- Cyclophosphamide
- Questionnaire Administration
Breakdown of trials Robert J. Hayashi has run
Cancer
Solid Tumors
Brain Tumor
Osteosarcoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Robert J. Hayashi specialize in?
Robert J. Hayashi focuses on Cancer and Solid Tumors. In particular, much of their work with Cancer has involved Stage I patients, or patients who are Stage IV.
Is Robert J. Hayashi currently recruiting for clinical trials?
Yes, Robert J. Hayashi is currently recruiting for 16 clinical trials in Saint Louis Missouri. If you're interested in participating, you should apply.
Are there any treatments that Robert J. Hayashi has studied deeply?
Yes, Robert J. Hayashi has studied treatments such as Nivolumab, Etoposide, Vincristine Sulfate.
What is the best way to schedule an appointment with Robert J. Hayashi?
Apply for one of the trials that Robert J. Hayashi is conducting.
What is the office address of Robert J. Hayashi?
The office of Robert J. Hayashi is located at: Washington University School of Medicine, Saint Louis, Missouri 63110 United States. This is the address for their practice at the Washington University School of Medicine.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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