Rajen Mody MBBS | Clinical Provider ...

Dr. Rajen Mody, MD, MS

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C S Mott Children's Hospital

Expert in Neuroblastoma
Expert in Cancer
52 reported clinical trials
85 drugs studied

About Rajen Mody, MD, MS

Education:

  • Earned an MD (Doctor of Medicine).
  • Holds an MS (Master of Science).

Experience:

  • Serves as Division Chief and Fellowship Program Director at the Pediatric Hematology/Oncology Fellowship Program, C.S. Mott Children's Hospital, University of Michigan.
  • Recognized for expertise in pediatric hematology and oncology, covering both non-malignant and malignant disorders.
  • Instrumental in developing a fellowship program aimed at nurturing future scientific investigators in pediatric hematology.
  • Engages in cutting-edge research and clinical care, including precision medicine and genomic sequencing, for children.

Area of expertise

1Neuroblastoma
Global Leader
Rajen Mody, MD, MS has run 28 trials for Neuroblastoma. Some of their research focus areas include:
MYC positive
Stage IV
BRD4 positive
2Cancer
Global Leader
Rajen Mody, MD, MS has run 24 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage I
Stage II

Affiliated Hospitals

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C S Mott Children's Hospital
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University Of Michigan

Clinical Trials Rajen Mody, MD, MS is currently running

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CBL0137

for Cancer

This trial tests CBL0137, a drug that blocks signals inside cancer cells, in patients whose solid tumors, including CNS tumors or lymphoma, have returned or not responded to treatment. By interfering with the cells' internal communication, the drug aims to stop their growth and cause them to die. CBL0137, also known as Curaxin, has shown antitumor activity in multiple cancers, including glioblastoma, renal cell carcinoma, melanoma, neuroblastoma, and small cell lung cancer.
Recruiting1 award Phase 1 & 213 criteria
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Levocarnitine

for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma

This phase III trial compares the effect of adding levocarnitine to standard chemotherapy versus (vs.) standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.
Recruiting2 awards Phase 3

More about Rajen Mody, MD, MS

Clinical Trial Related8 years of experience running clinical trials · Led 52 trials as a Principal Investigator · 12 Active Clinical Trials
Treatments Rajen Mody, MD, MS has experience with
  • Dinutuximab
  • Cytology Specimen Collection Procedure
  • Laboratory Biomarker Analysis
  • Cyclophosphamide
  • Temozolomide
  • Larotrectinib

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