Paul Celano, MD, FACP, FASCO | GBMC ...

Dr. Paul Celano

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Greater Baltimore Medical Center

Studies Ovarian Cancer
Studies Bladder Cancer
7 reported clinical trials
22 drugs studied

Area of expertise

1

Ovarian Cancer

Paul Celano has run 4 trials for Ovarian Cancer. Some of their research focus areas include:

Stage III
Stage II
Stage IV
2

Bladder Cancer

Paul Celano has run 3 trials for Bladder Cancer. Some of their research focus areas include:

Stage IV
HER2 positive
Stage III

Affiliated Hospitals

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Greater Baltimore Medical Center

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Greater Baltimore Medical Center (GBMC) - Sandra & Malcolm Berman Cancer Institute

Clinical Trials Paul Celano is currently running

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Disitamab Vedotin + Pembrolizumab vs Chemotherapy

for Bladder Cancer

This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try to find out if the drugs disitamab vedotin with pembrolizumab works better than platinum-containing chemotherapy to treat patients with UC. This study will also test what side effects happen when participants take these drugs together. A side effect is anything a drug does to the body besides treating the disease. Participants in this study will have cancer that has spread through the body (metastatic) or spread near where it started (locally advanced). In this study, there are 2 different groups. Participants will be assigned to a group randomly. Participants in the disitamab vedotin arm will get the study drug disitamab vedotin once every two weeks and pembrolizumab once every 6 weeks. Participants in the standard of care arm will get gemcitabine once a week for 2 weeks with either cisplatin or carboplatin once every 3 weeks.

Recruiting

2 awards

Phase 3

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Immunotherapy + Targeted Therapy

for Genitourinary Cancers

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.

Recruiting

1 award

Phase 2

21 criteria

More about Paul Celano

Clinical Trial Related

3 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Paul Celano has experience with

  • Nirogacestat
  • Quality-of-Life Assessment
  • Biospecimen Collection
  • Questionnaire Administration
  • Data Collection
  • Blood Sample Collection

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