Dr. Oak Forest Site PI

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Oak Forest Location

Studies Cystoid Macular Edema
Studies Retinal Disease
1 reported clinical trial
1 drug studied

Affiliated Hospitals

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University Retina And Macula Associates, PC

Clinical Trials Oak Forest Site PI is currently running

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RGX-314 Gene Therapy

for Diabetic Retinopathy

ABBV-RGX-314 is being developed as a novel, potential one-time gene therapy treatment for the treatment of Diabetic Retinopathy (DR) with and without Center-Involved Diabetic Macular Edema (CI-DME). DR is a chronic and progressive complication of diabetes mellitus. It is a sight-threatening disease characterized in the early stages by neuronal and vascular dysfunction in the retina, and later by neovascularization that leads to further deterioration of functional vision. Despite the availability of current treatments, diabetic retinopathy remains the leading cause of vision loss in working-age adults, those between the ages of 20 and 74. Existing treatment with anti-VEGF agents, although shown to be effective, are limited by short therapeutic half-lives, which then require frequent intravitreal injections over the patient's lifetime, resulting in increased risk of associated adverse events and significant treatment burden. Due to the burden of treatment, patients often do not closely adhere to treatment regimens and experience sub-optimal outcomes and a decline in vision.
Recruiting1 award Phase 22 criteria

More about Oak Forest Site PI

Clinical Trial Related4 years of experience running clinical trials · Led 1 trial as a Principal Investigator · 1 Active Clinical Trial
Treatments Oak Forest Site PI has experience with
  • RGX-314
Breakdown of trials Oak Forest Site PI has run
Cystoid Macular Edema
Retinal Disease
Retinopathies
Choroidal Effusion
Edema

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Veeral Sheth, MDUniversity Retina and Macula Associates

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