Dr. Nicole Shonka, MD
Claim this profileUniversity of Nebraska Medical Center
Studies Brain Tumor
Studies Glioblastoma
5 reported clinical trials
13 drugs studied
Area of expertise
1Brain Tumor
IDH positive
1p/19q co-deletion positive
SMO positive
2Glioblastoma
MET negative
Stage III
Stage IV
Affiliated Hospitals
Clinical Trials Nicole Shonka, MD is currently running
Multiple Targeted Therapies
for Meningioma
This trial studies four drugs to treat patients with worsening meningioma. These drugs work by blocking enzymes that the tumor cells need to grow. The trial focuses on patients whose tumors have specific genetic mutations.
Recruiting1 award Phase 210 criteria
APG-157 + Bevacizumab
for Brain Tumor
The goal of this interventional study is to evaluate the efficacy of APG-157 in combination with Bevacizumab in subjects with recurrent high-grade glioma. The main questions the study aims to answer are: * Progression-free and overall survival of patients receiving this combination; * Quality of Life (QOL); and * Tumor response on imaging The participants will take APG-157 daily by dissolving two pastilles in their mouth at around breakfast, lunch and dinner time (total of six pastilles per day). The pastilles dissolve in the mouth. The participants will continue to receive Bevacizumab as standard of care.
Recruiting1 award Phase 1 & 214 criteria
More about Nicole Shonka, MD
Clinical Trial Related9 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Nicole Shonka, MD has experience with
- APG-157
- Berubicin
- Lomustine
- Ipilimumab
- Nivolumab
- Radiation Therapy
Breakdown of trials Nicole Shonka, MD has run
Brain Tumor
Glioblastoma
Brain Cancer
Gliosarcoma
Meningioma
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