Dr. Naoko Takebe
Claim this profileNational Institutes of Health Clinical Center
Studies Pancreatic Cancer
Studies Cancer
7 reported clinical trials
13 drugs studied
Area of expertise
1Pancreatic Cancer
Stage IV
PIK3CB positive
PTEN positive
2Cancer
Stage IV
PIK3CB positive
PTEN positive
Affiliated Hospitals
Clinical Trials Naoko Takebe is currently running
Pelcitoclax + Cobimetinib
for Recurrent Ovarian and Endometrial Cancers
This trial tests the safety and best dose of two drugs, pelcitoclax and cobimetinib, in patients with recurring ovarian and endometrial cancers. Pelcitoclax helps kill cancer cells, and cobimetinib slows their growth. The goal is to find an effective dose and observe how well the combination works in shrinking or stabilizing tumors.
Recruiting1 award Phase 117 criteria
CA-4948 + Chemotherapy
for Pancreatic Cancer
This phase I trial tests the safety, side effects, and best dose of emavusertib (CA-4948) in combination with gemcitabine and nab-paclitaxel in treating patients with pancreatic ductal adenocarcinoma that has spread from where it first started (primary site) to other places in the body (metastatic) or cannot be removed by surgery (unresectable). CA-4948 is in a class of medications called kinase inhibitors. It works by blocking the action of abnormal proteins called interleukin-1 receptor-associated kinase 4 (IRAK4) and FMS-like tyrosine kinase 3 (FLT3) that signal cells to multiply. This may help keep cancer cells from growing. The usual approach for patients with pancreatic ductal adenocarcinoma is treatment with chemotherapy drugs gemcitabine and nab-paclitaxel. Gemcitabine is a chemotherapy drug that blocks the cells from making DNA and may kill cancer cells. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Nab-paclitaxel is an albumin-stabilized nanoparticle formulation of paclitaxel which may have fewer side effects and work better than other forms of paclitaxel. Giving CA-4948 in combination with gemcitabine and nab-paclitaxel may shrink or stabilize metastatic or unresectable pancreatic ductal adenocarcinoma.
Recruiting1 award Phase 120 criteria
More about Naoko Takebe
Clinical Trial Related8 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Naoko Takebe has experience with
- Nivolumab
- Ipilimumab
- Atezolizumab
- Tiragolumab
- Docetaxel
- PI3Kbeta Inhibitor AZD8186
Breakdown of trials Naoko Takebe has run
Pancreatic Cancer
Cancer
Ovarian Cancer
Solid Tumors
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Naoko Takebe specialize in?
Naoko Takebe focuses on Pancreatic Cancer and Cancer. In particular, much of their work with Pancreatic Cancer has involved Stage IV patients, or patients who are PIK3CB positive.
Is Naoko Takebe currently recruiting for clinical trials?
Yes, Naoko Takebe is currently recruiting for 3 clinical trials in Bethesda Maryland. If you're interested in participating, you should apply.
Are there any treatments that Naoko Takebe has studied deeply?
Yes, Naoko Takebe has studied treatments such as Nivolumab, Ipilimumab, Atezolizumab.
What is the best way to schedule an appointment with Naoko Takebe?
Apply for one of the trials that Naoko Takebe is conducting.
What is the office address of Naoko Takebe?
The office of Naoko Takebe is located at: National Institutes of Health Clinical Center, Bethesda, Maryland 20892 United States. This is the address for their practice at the National Institutes of Health Clinical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.