Dr. Michael Offin
Claim this profileMemorial Sloan Kettering Cancer Center
Studies Malignant Pleural Mesothelioma
Studies Mesothelioma
5 reported clinical trials
12 drugs studied
Area of expertise
1Malignant Pleural Mesothelioma
systemic
unresectable
2Mesothelioma
systemic
unresectable
Affiliated Hospitals
Clinical Trials Michael Offin is currently running
Sacituzumab Govitecan
for Mesothelioma
Participants will receive sacituzumab govitecan until their disease gets worse (progresses), they have severe side effects and cannot continue study treatment, or the participants or the study doctor thinks it's in your best interest to stop treatment.
Recruiting1 award Phase 24 criteria
BDTX-4933
for Cancer
BDTX-4933-101 is a first-in-human, open-label, Phase 1 dose escalation and an expansion cohort study designed to evaluate the safety and tolerability, maximum tolerated dose (MTD) and the preliminary recommended Phase 2 dose (RP2D), and antitumor activity of BDTX-4933. The study population for the Dose Escalation part of the study comprises adults with recurrent advanced/metastatic non-small cell lung cancer (NSCLC) harboring KRAS non-G12C mutations, BRAF, or CRAF (RAF1) mutations, advanced/metastatic melanoma harboring BRAF or NRAS mutations, histiocytic neoplasms harboring BRAF, CRAF, or NRAS mutations, and other solid tumors harboring BRAF mutations. The study population for the Dose Expansion part of the study comprises adults with recurrent advanced/metastatic NSCLC harboring KRAS non-G12C mutations. All patients will self-administer BDTX-4933 orally in 28-day cycles until disease progression, toxicity, withdrawal of consent, or termination of the study.
Recruiting1 award Phase 1
More about Michael Offin
Clinical Trial Related8 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Michael Offin has experience with
- Cisplatin Or Carboplatin
- Nivolumab
- Pemetrexed
- Surgery
- Sacituzumab Govitecan
- LTT462
Breakdown of trials Michael Offin has run
Malignant Pleural Mesothelioma
Mesothelioma
Lung Cancer
Non-Small Cell Lung Cancer
Melanoma
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