Meghana Raghavendra MD | Indianapolis ...

Dr. Meghana Raghavendra

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Franciscan Health Indianapolis

Studies Colon Cancer
Studies Colorectal Cancer
13 reported clinical trials
30 drugs studied

Area of expertise

1

Colon Cancer

Meghana Raghavendra has run 5 trials for Colon Cancer. Some of their research focus areas include:

Stage IV
Stage III
BRAF negative
2

Colorectal Cancer

Meghana Raghavendra has run 3 trials for Colorectal Cancer. Some of their research focus areas include:

Stage IV
Stage III
dMMR negative

Affiliated Hospitals

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Franciscan Health Indianapolis

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Franciscan Health Mooresville

Clinical Trials Meghana Raghavendra is currently running

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Nivolumab + Ipilimumab + Sargramostim

for Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable) and that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Colony-stimulating factors, such as sargramostim, may increase the production of white blood cells. It is not yet known whether nivolumab and ipilimumab are more effective with or without sargramostim in treating patients with melanoma.

Recruiting

1 award

Phase 2 & 3

23 criteria

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Relatlimab + Nivolumab

for Recurrent Glioblastoma

This phase II trial compares the safety, side effects and effectiveness of anti-lag-3 (relatlimab) and anti-PD-1 blockade (nivolumab) to standard of care lomustine for the treatment of patients with glioblastoma that has come back after a period of improvement (recurrent). Relatlimab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the tumor, and may interfere with the ability of tumor cells to grow and spread. Lomustine is a chemotherapy drug and in a class of medications called alkylating agents. It damages the cell's deoxyribonucleic acid and may kill tumor cells. Giving relatlimab and nivolumab may be safe, tolerable, and/or effective compared to standard of care lomustine in treating patients with recurrent glioblastoma.

Recruiting

1 award

Phase 2

15 criteria

More about Meghana Raghavendra

Clinical Trial Related

6 years of experience running clinical trials · Led 13 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Meghana Raghavendra has experience with

  • Nivolumab
  • Fluorouracil
  • Bevacizumab
  • Leucovorin Calcium
  • Irinotecan Hydrochloride
  • Ipilimumab

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