Dr. Meghan J Mooradian, MD
Claim this profileMassachusetts General Hospital Cancer Center
Studies Melanoma
Studies Lung Cancer
5 reported clinical trials
9 drugs studied
Area of expertise
1Melanoma
Stage IV
Stage III
2Lung Cancer
Stage IV
Affiliated Hospitals
Clinical Trials Meghan J Mooradian, MD is currently running
Cryoablation + Ipilimumab + Nivolumab
for Melanoma
The aim of this study is to find out whether the combination of two approved drugs, ipilimumab and nivolumab, in combination with cryoablation are safe and effective for participants who have an unresectable melanoma that is resistant, or is growing, after receiving immunotherapy with a PD-1 inhibitor. The names of the study interventions involved in this study are: * Cryoablation (an interventional radiology procedure that freezes part of a tumor) * Ipilimumab (an immunotherapy) * Nivolumab (an immunotherapy)
Recruiting1 award Phase 221 criteria
SX-682 + Pembrolizumab
for Melanoma
Cancers attract myeloid-derived suppressor cells (MDSCs) that prevent our own immune responses from destroying the cancer. This study will be the first study to begin to determine if the newly discovered drug SX-682 can block cancers from attracting MDSCs. This first study will enroll participants with melanoma, as melanoma cancer has been shown to be able to attract MDSCs. The study will begin to determine if SX-682 is a safe and effective treatment of melanoma. It is thought that SX-682 will block MDSCs from going to the cancer, and thus will allow a patient's own immune system to attack the cancer. The first participants enrolled in the study will receive for 21 days SX-682 as monotherapy. After 21 days participants will receive pembrolizumab therapy (an approved immunotherapy for melanoma) in combination with SX-682 for up to approximately 2 years. Once the safe dose level of SX-682 in combination with pembrolizumab is determined, the remaining participants will be enrolled at the highest safe dose level of SX-682, in combination with pembrolizumab. These participants will receive the combination therapy and be evaluated in the study for approximately 2 years.
Recruiting1 award Phase 121 criteria
More about Meghan J Mooradian, MD
Clinical Trial Related2 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Meghan J Mooradian, MD has experience with
- Cryoablation
- Ipilimumab
- Nivolumab
- Evaluation Of CtDNA
- Core Needle Biopsy
- Pembrolizumab
Breakdown of trials Meghan J Mooradian, MD has run
Melanoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Meghan J Mooradian, MD specialize in?
Meghan J Mooradian, MD focuses on Melanoma and Lung Cancer. In particular, much of their work with Melanoma has involved Stage IV patients, or patients who are Stage III.
Is Meghan J Mooradian, MD currently recruiting for clinical trials?
Yes, Meghan J Mooradian, MD is currently recruiting for 2 clinical trials in Boston Massachusetts. If you're interested in participating, you should apply.
Are there any treatments that Meghan J Mooradian, MD has studied deeply?
Yes, Meghan J Mooradian, MD has studied treatments such as Cryoablation, Ipilimumab, Nivolumab.
What is the best way to schedule an appointment with Meghan J Mooradian, MD?
Apply for one of the trials that Meghan J Mooradian, MD is conducting.
What is the office address of Meghan J Mooradian, MD?
The office of Meghan J Mooradian, MD is located at: Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114 United States. This is the address for their practice at the Massachusetts General Hospital Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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