Dr. Mauro Schenone, MD
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Mayo Clinic
Mayo Clinic In Rochester, Minnesota
Clinical Trials Mauro Schenone, MD is currently running
Amnioinfusion
for Pulmonary Hypoplasia Due to Renal Conditions
Congenital lower urinary tract obstruction (LUTO) is a heterogeneous group of congenital anomalies that lead bladder outlet obstruction. If a complete obstruction is present, the perinatal mortality is estimated to be as high as 90% because of severe pulmonary hypoplasia due to the lack of amniotic fluid. Survivors have significant risk of renal impairment (90%) requiring dialysis or renal transplantation if no fetal intervention is performed. Renal agenesis is the congenital absence of one or both kidneys due to complete failure of the kidney to form. As many as 33% of fetuses with bilateral renal agenesis are stillborn, and the rest of them die immediately after birth due to severe pulmonary hypoplasia. The objective of the serial amnioinfusions for fetuses with these conditions will be to reduce the severity of pulmonary hypoplasia (regenerating the lung functionality) and therefore increase the chance that the newborn survives to begin peritoneal dialysis. Although there is initial evidence that serial amnioinfusions are feasible for the pregnant women and the fetuses, there is still a need to have a prospective clinical trial to confirm the hypothesis that serial amnioinfusions could prevent severe pulmonary hypoplasia allowing the newborns with bilateral renal agenesis or severe LUTO to survive to begin peritoneal dialysis. Therefore, the investigators aim to study the hypothesis that serial amnioinfusions for fetuses with severe LUTO and renal failure and those with bilateral renal agenesis will reduce the severity of pulmonary hypoplasia and therefore increase the chance that the newborn survives to begin peritoneal dialysis.
Recruiting
1 award
Phase 1
8 criteria
Fetal Endoscopic Tracheal Occlusion
for Congenital Diaphragmatic Hernia
The purpose of this research is to gather information on the safety and effectiveness of a procedure called Fetoscopic Endoluminal Tracheal Occlusion (FETO) at Mayo Clinic. The intent of the FETO procedure is to improve development of the lungs in fetuses diagnosed with severe congenital diaphragmatic hernia (CDH).
Recruiting
1 award
N/A
More about Mauro Schenone, MD
Clinical Trial Related
3 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Mauro Schenone, MD has experience with
- Karl Storz New Generation Fetoscope
- Serial Amnioinfusions
- Fetal Endoscopic Tracheal Occlusion
- Fetal Aortic Valvuloplasty
- Blood And Placenta Specimen Collection
Breakdown of trials Mauro Schenone, MD has run
Bladder outlet obstruction
Congenital Diaphragmatic Hernia
In Utero Procedure
Aniridia, Renal Agenesis, Psychomotor Retardation
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mauro Schenone, MD specialize in?
Mauro Schenone, MD focuses on Bladder outlet obstruction and Congenital Diaphragmatic Hernia. In particular, much of their work with Bladder outlet obstruction has involved treating patients, or patients who are undergoing treatment.
Is Mauro Schenone, MD currently recruiting for clinical trials?
Yes, Mauro Schenone, MD is currently recruiting for 2 clinical trials in Rochester Minnesota. If you're interested in participating, you should apply.
Are there any treatments that Mauro Schenone, MD has studied deeply?
Yes, Mauro Schenone, MD has studied treatments such as Karl Storz New Generation Fetoscope, Serial Amnioinfusions, Fetal Endoscopic Tracheal Occlusion.
What is the best way to schedule an appointment with Mauro Schenone, MD?
Apply for one of the trials that Mauro Schenone, MD is conducting.
What is the office address of Mauro Schenone, MD?
The office of Mauro Schenone, MD is located at: Mayo Clinic Rochester, Rochester, Minnesota 55905 United States. This is the address for their practice at the Mayo Clinic Rochester.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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