Dr. Mary-Elizabeth Percival

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Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium

Studies Acute Myelogenous Leukemia
Studies Acute Myeloid Leukemia
3 reported clinical trials
5 drugs studied

Area of expertise

1Acute Myelogenous Leukemia
Mary-Elizabeth Percival has run 3 trials for Acute Myelogenous Leukemia. Some of their research focus areas include:
CD33 positive
Stage I
Stage II
2Acute Myeloid Leukemia
Mary-Elizabeth Percival has run 3 trials for Acute Myeloid Leukemia. Some of their research focus areas include:
CD33 positive
Stage I
Stage II

Affiliated Hospitals

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Fred Hutchinson Cancer Research Center/University Of Washington Cancer Consortium
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Fred Hutch/University Of Washington Cancer Consortium

Clinical Trials Mary-Elizabeth Percival is currently running

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Gemtuzumab Ozogamicin

for Acute Myeloid Leukemia

This phase II trial studies the how well fractionated gemtuzumab ozogamicin works in treating measurable residual disease in patients with acute myeloid leukemia. Gemtuzumab ozogamicin is a monoclonal antibody, called gemtuzumab, linked to a chemotherapy drug, called ozogamicin. Gemtuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD33 receptors, and delivers a chemotherapy known as calicheamicin to kill them.
Recruiting1 award Phase 2
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FLAG-Ida + Pivekimab

for Acute Myeloid Leukemia

This phase I trial finds the best dose of PVEK when given together with fludarabine, cytarabine, granulocyte colony-stimulating factor (G-CSF), and idarubicin, (FLAG-Ida) regimen and studies the effectiveness of this combination therapy in treating patients with newly diagnosed adverse risk acute myeloid leukemia (AML) and other high-grade myeloid neoplasms. PVEK is a monoclonal antibody linked to a chemotherapy drug. PVEK is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD123 receptors, and delivers the chemotherapy drug to kill them. Chemotherapy drugs, such as idarubicin, fludarabine, high-dose cytarabine work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. G-CSF helps the bone marrow make more white blood cells in patients with low white blood cell count due to cancer treatment. Giving PVEK with the FLAG-Ida regimen may be a safe and effective treatment for patients with acute myeloid leukemia and other high-grade myeloid neoplasms.
Recruiting1 award Phase 113 criteria

More about Mary-Elizabeth Percival

Clinical Trial Related6 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Mary-Elizabeth Percival has experience with
  • Gemtuzumab Ozogamicin
  • FLAG-Ida
  • Pivekimab Sunirine
  • 5-azacitidine
  • APG-115

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