Dr. Maisa Nabil Feghali, MD ...

Dr. Maisa Feghali, MD

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Magee Womens Hospital of UPMC

Studies Gestational Diabetes
Studies Thyroid Dysfunction
5 reported clinical trials
6 drugs studied

Affiliated Hospitals

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Magee Women's Hospital Of UPMC
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University Of Pittsburgh

Clinical Trials Maisa Feghali, MD is currently running

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Exenatide

for Gestational Diabetes

This study is being done to study how exenatide, an FDA-approved drug that lowers blood sugar in non-pregnant patients with type II diabetes, works in pregnant women. To do this, the investigators will study the drug's pharmacokinetics (what the body does to the drug; specifically, how quickly your body breaks down and excretes exenatide) and pharmacodynamics (what the drug does to the body; specifically, how effectively exenatide helps the participants' pancreas secrete insulin and how well it controls blood sugar after a meal). There are only two main drug therapies (insulin injections and glyburide pills) currently used for gestational diabetes and not all women achieve good enough blood sugar control without side effects. Therefore, the investigators hope to find out if exenatide might also be helpful in gestational diabetes.
Recruiting3 awards Phase 44 criteria
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Metformin vs Insulin

for Gestational Diabetes

This is a non-inferiority patient-centered and pragmatic comparative-effectiveness pregnancy randomized controlled trial (RCT) with postpartum maternal and child follow-up through 2 years of 1,572 individuals with gestational diabetes mellitus (GDM) randomized to oral metformin versus injectable insulin. This study will determine if metformin is not inferior to insulin in reducing adverse pregnancy outcomes, is comparably safe for exposed individuals and children, and if patient-reported factors, including facilitators of and barriers to use, differ between metformin and insulin. A total of 1,572 pregnant individuals with GDM who need pharmacotherapy will be recruited at 20 U.S. sites using consistent treatment criteria to metformin versus insulin. Participants and their children will be followed through delivery to two years postpartum.
Recruiting3 awards Phase 42 criteria

More about Maisa Feghali, MD

Clinical Trial Related7 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Maisa Feghali, MD has experience with
  • Metformin
  • Insulin
  • Glyburide
  • Exenatide
  • Intensive Glycemic Targets
  • Standard Glycemic Targets

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