Dr. Lisa Barroilhet
Claim this profileUniversity of Wisconsin Carbone Cancer Center
Studies Ovarian Cancer
Studies Cervical Adenocarcinoma
15 reported clinical trials
28 drugs studied
Area of expertise
1Ovarian Cancer
Stage III
Stage IV
BRCA1 positive
2Cervical Adenocarcinoma
Stage III
Stage IV
Stage II
Affiliated Hospitals
Clinical Trials Lisa Barroilhet is currently running
RG1-VLP Vaccine
for HPV-Related Cancers
This phase I trial tests the safety, side effects, and best dose of RG1-virus-like particle (VLP) in preventing human papillomavirus (HPV)-related cancers in women. RG1-VLP is a vaccine that aims to protect against rare HPV types not targeted by currently approved HPV vaccines. HPV is a common sexually-transmitted infection that can cause certain genital and oral cancers. RG1-VLP contains a protein of HPV type 16 (HPV16) with a slightly different structure than the licensed Gardasil-9 vaccine. Gardasil-9 is approved by the Federal Drug Administration to help protect against diseases caused by some types of HPV. Gardasil-9 also contains 9 different HPV proteins. Both vaccines contain alum to stimulate the immune system. The usual approach for the prevention of HPV-related cancers for patients who are at increased risk is to consider the currently approved HPV vaccine like Gardasil-9, as well as to be followed closely by their doctor to watch for the development of cancer via routine pap smears. This trial may allow researchers to find out whether the RG1-VLP vaccine can safely trigger an immune response against HPV in healthy women and if it is better or worse than the usual approach for the prevention of HPV-related cancers.
Recruiting0 awards Phase 1
ZN-c3
for Serous Carcinoma
This is a multi-part Phase 2 study to evaluate the efficacy and safety of azenosertib (ZN-c3) in subjects with Platinum-Resistant, High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer. Part 2 of the study will be conducted in subjects whose tumors are Cyclin E1 positive as determined by central review using the Sponsor's investigational clinical trial assay.
Recruiting1 award Phase 21 criteria
More about Lisa Barroilhet
Clinical Trial Related6 years of experience running clinical trials · Led 15 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Lisa Barroilhet has experience with
- Paclitaxel
- Pegylated Liposomal Doxorubicin Hydrochloride
- Laparotomy
- Chemotherapy
- Minimally Invasive Surgery
- RG1-VLP Vaccine
Breakdown of trials Lisa Barroilhet has run
Ovarian Cancer
Cervical Adenocarcinoma
Ovarian Carcinoma
Serous Cystadenocarcinoma
Clear Cell Adenocarcinoma
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