Dr. Leonard M. Klein, MD | Niles, IL ...

Dr. Leonard Klein

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Illinois Cancer Specialists

Studies Lymphoma
Studies B-Cell Lymphoma
10 reported clinical trials
26 drugs studied

Area of expertise

1Lymphoma
Leonard Klein has run 3 trials for Lymphoma. Some of their research focus areas include:
CD30 negative
HTLV-1 positive
2B-Cell Lymphoma
Leonard Klein has run 2 trials for B-Cell Lymphoma.

Affiliated Hospitals

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Illinois Cancer Specialists
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Illinois Cancer Specialist

Clinical Trials Leonard Klein is currently running

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Lenalidomide + Dexamethasone +/- Daratumumab

for Multiple Myeloma

This phase III trial studies how well lenalidomide and dexamethasone works with or without daratumumab in treating patients with high-risk smoldering myeloma. Drugs used in chemotherapy, such as lenalidomide and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as daratumumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Giving lenalidomide and dexamethasone with daratumumab may work better in treating patients with smoldering myeloma.
Recruiting2 awards Phase 312 criteria
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Tazemetostat + Lenalidomide + Rituximab

for Follicular Lymphoma

The participants of this study would have relapsed/refractory follicular lymphoma. Follicular lymphoma is a type of blood cancer. It is referred to as 'relapsed' when the disease has come back after a period of improvement after that follows a treatment regimen and 'refractory' when treatment no longer works. Stage 1 of this trial will study the safety and the level that adverse effects of each of the study drug combinations can be tolerated (known as tolerability). It is also designed to establish a recommended study drug dosage for stage 2 and 3. Stage 1 of the study is completed. Stages 2 and 3 will evaluate and compare how long participants live without their disease getting worse when receiving the study drug in combination with other drug treatment versus the placebo (dummy drug) in combination with other drug treatment.
Recruiting1 award Phase 34 criteria

More about Leonard Klein

Clinical Trial Related5 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Leonard Klein has experience with
  • Lenalidomide
  • Rituximab
  • Cyclophosphamide
  • Brentuximab Vedotin
  • Abemaciclib
  • Selinexor

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