Dr. Laura McAdam, MD
Claim this profileHolland Bloorview Kids Rehabilitation Hospital
Studies Muscular Dystrophy
Studies Spinal Muscular Atrophy
3 reported clinical trials
4 drugs studied
Affiliated Hospitals
Clinical Trials Laura McAdam, MD is currently running
Givinostat
for Duchenne Muscular Dystrophy
This is a randomised, double-blind, placebo-controlled, multicentre study to evaluate the efficacy, safety, and tolerability of givinostat in non-ambulant male paediatric (aged 9 to \<18 years) patients with DMD. 138 patients will be randomised 2:1 to givinostat or placebo and will be treated for 18 months. * Planned screening duration: approximately 4 weeks (±14 days) * Planned treatment duration: 18 months (approximately 72 weeks) * Planned follow-up duration: 4 weeks (±7 days) (for patients not participating in the long-term safety study) * Total duration of study participation: up to 83 weeks (ie, 20-21 months)
Recruiting1 award Phase 3
Rehabilitation
for Spinal Muscular Atrophy
This trial is testing a rehabilitation program for young children with Spinal Muscular Atrophy (SMA) who have received genetic treatments. The program includes regular physical and occupational therapy sessions and home exercises. The goal is to see if this helps improve their physical abilities. A supervised, home-based progressive resistance training exercise program is feasible, safe, and well tolerated in children with SMA.
Recruiting1 award N/A8 criteria
More about Laura McAdam, MD
Clinical Trial Related4 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Laura McAdam, MD has experience with
- Rehabilitation Intervention
- Online Survey
- Qualitative Interviews
- Givinostat
Breakdown of trials Laura McAdam, MD has run
Muscular Dystrophy
Spinal Muscular Atrophy
Optic Nerve Atrophy
Muscle Atrophy
Myopathy
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