Dr. LaQuisa HIll, MD
Claim this profileBaylor College of Medicine
Studies Lymphoma
Studies Acute Lymphoblastic Leukemia
5 reported clinical trials
7 drugs studied
Area of expertise
1Lymphoma
CD7 positive
CD5 positive
CD30 positive
2Acute Lymphoblastic Leukemia
CD7 positive
Affiliated Hospitals
Clinical Trials LaQuisa HIll, MD is currently running
MB-105
for T-cell Lymphoma
This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon two-stage optimal design.
Recruiting1 award Phase 26 criteria
CAR T-cell Therapy
for Acute Myeloid Leukemia
Patients eligible for this study have a type of blood cancer Acute Myeloid Leukemia (AML) which has come back or has not gone away after treatment. The body has different ways of fighting disease and infection, and this research study combines two different ways of fighting cancer with antibodies and T cells with the hope that they will work together. T cells (also called T lymphocytes) are special infection-fighting blood cells that can kill other cells including tumor cells. Antibodies are types of proteins that protect the body from bacterial and other infectious diseases. Both antibodies and T cells have been used to treat patients with cancers; they have shown promise, but have not been strong enough to cure most patients when used alone. T lymphocytes can kill tumor cells but there normally are not enough of them to kill all the tumor cells. Some researchers have taken T cells from a person's blood, grown more of them in the laboratory and then given them back to the person. The antibody used in this study targets CLL-1. This antibody sticks to AML cells because of a substance (protein) on the outside of these cells called CLL-1. For this study, the antibody to CLL-1 has been changed so that instead of floating free in the blood, it is now joined to the T cells. When T-cells contain an antibody that is joined to them, they are called chimeric antigen receptor T-cells or CAR-T cells. In the laboratory, the investigators have also found that T cells work better if proteins that stimulate T cells are also added, such as one called CD28. Adding the CD28 makes the cells grow better and last longer in the body, thus giving the cells a better chance of killing the leukemia or lymphoma cells. In this study we are going to attach the CLL-1 chimeric receptor that has CD28 added to it to the patient's T cells. We will then test how long the cells last. These CLL-1 chimeric antigen receptor T cells with CD28 are investigational products not approved by the Food and Drug Administration.
Recruiting1 award Phase 110 criteria
More about LaQuisa HIll, MD
Clinical Trial Related1 year of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments LaQuisa HIll, MD has experience with
- CD7.CAR/28zeta CAR T Cells
- Cyclophosphamide
- Fludarabine
- Donor Search Prognosis Score
- MB-105
- CLL-1.CAR T Cells
Breakdown of trials LaQuisa HIll, MD has run
Lymphoma
Acute Lymphoblastic Leukemia
T-Lymphoblastic Leukemia/Lymphoma
Acute Myeloid Leukemia
Lymphoid Leukemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does LaQuisa HIll, MD specialize in?
LaQuisa HIll, MD focuses on Lymphoma and Acute Lymphoblastic Leukemia. In particular, much of their work with Lymphoma has involved CD7 positive patients, or patients who are CD5 positive.
Is LaQuisa HIll, MD currently recruiting for clinical trials?
Yes, LaQuisa HIll, MD is currently recruiting for 3 clinical trials in Houston Texas. If you're interested in participating, you should apply.
Are there any treatments that LaQuisa HIll, MD has studied deeply?
Yes, LaQuisa HIll, MD has studied treatments such as CD7.CAR/28zeta CAR T cells, Cyclophosphamide, Fludarabine.
What is the best way to schedule an appointment with LaQuisa HIll, MD?
Apply for one of the trials that LaQuisa HIll, MD is conducting.
What is the office address of LaQuisa HIll, MD?
The office of LaQuisa HIll, MD is located at: Baylor College of Medicine, Houston, Texas 77030 United States. This is the address for their practice at the Baylor College of Medicine.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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