Dr. Lana Castellucci, MD
Claim this profileThe Ottawa Hospital - General Campus
Studies Venous Thromboembolism
Studies Deep Vein Thrombosis
5 reported clinical trials
7 drugs studied
Affiliated Hospitals
Clinical Trials Lana Castellucci, MD is currently running
Heparin
for Community-Acquired Pneumonia
This trial is testing if higher doses of heparin, a blood thinner, can help patients hospitalized with pneumonia. These patients often have blood clot complications that worsen their condition. By preventing these clots, heparin might improve their recovery and reduce severe outcomes. Heparin has been shown to reduce the risk of blood clots in various patients, including those hospitalized for medical conditions and surgeries.
Recruiting2 awards Phase 35 criteria
Blood Thinners
for Atrial Fibrillation
Atrial Fibrillation (AF) affects 200,000 Canadians and increases risk of stroke, morbidity and mortality. Having a stroke can affect a patient's ability to speak, eat, walk, work, care for themselves, and interact with others. Not only can it ruin one's life, but it can also be fatal. A stroke occurs when blood flow to the brain is blocked by a clot, depriving brain cells of oxygen. In people with atrial fibrillation, blood flow is sluggish in the top chambers of the heart, and blood clots can form there. When a piece of a clot breaks off, it can travel to the brain and cause a stroke. That's where blood thinners come in. Blood thinners, or anticoagulants, decrease the chances of blood clots forming in the heart, reducing the risk of stroke. Studies show that blood thinners are highly effective at reducing the risk of stroke by up to 95%. The conventional blood thinner is warfarin, taken by mouth. Warfarin requires regular blood tests to make sure a patient getting the correct dose. The patient also may have to avoid certain foods since the medication can interact with them. Newer blood thinners, known as direct-oral anticoagulants (DOACs) are available, which do not require regular blood tests and do not interact with foods. Two of the new blood thinners are called rivaroxaban and apixaban. Like warfarin, they can be taken by mouth, and studies have shown them to be as effective as warfarin. Both rivaroxaban and apixaban have been approved for stroke prevention in AF by Health Canada. However, there have been no direct head-to-head comparisons of these two anticoagulants, meaning comparative safety data is not available. Increasing use of DOACs for stroke prevention in AF and patient values around bleeding highlight the need for a comparison trial to ensure patients receive the anticoagulant with the greatest balance of benefit to potential harm. The trial is to assess bleeding rates and superiority of using apixaban versus rivaroxaban in patients with non-valvular atrial fibrillation.
Recruiting3 awards Phase 42 criteria
More about Lana Castellucci, MD
Clinical Trial Related7 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Lana Castellucci, MD has experience with
- Apixaban
- Rivaroxaban
- Medical Mask
- N95 Respirator
- Alteplase
- Placebo
Breakdown of trials Lana Castellucci, MD has run
Venous Thromboembolism
Deep Vein Thrombosis
Atrial Fibrillation
N95 Respirator Mask
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Lana Castellucci, MD specialize in?
Lana Castellucci, MD focuses on Venous Thromboembolism and Deep Vein Thrombosis. In particular, much of their work with Venous Thromboembolism has involved treating patients, or patients who are undergoing treatment.
Is Lana Castellucci, MD currently recruiting for clinical trials?
Yes, Lana Castellucci, MD is currently recruiting for 3 clinical trials in Ottawa Ontario. If you're interested in participating, you should apply.
Are there any treatments that Lana Castellucci, MD has studied deeply?
Yes, Lana Castellucci, MD has studied treatments such as Apixaban, Rivaroxaban, Medical Mask.
What is the best way to schedule an appointment with Lana Castellucci, MD?
Apply for one of the trials that Lana Castellucci, MD is conducting.
What is the office address of Lana Castellucci, MD?
The office of Lana Castellucci, MD is located at: The Ottawa Hospital - General Campus, Ottawa, Ontario K1H 8L6 Canada. This is the address for their practice at the The Ottawa Hospital - General Campus.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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