Kiran Naqvi | UCI Health | Orange ...

Dr. Kiran Naqvi

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M D Anderson Cancer Center

Studies Acute Myeloid Leukemia
Studies Acute Myelogenous Leukemia
5 reported clinical trials
10 drugs studied

Affiliated Hospitals

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M D Anderson Cancer Center

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MD Anderson Regional Care Center-Bay Area

Clinical Trials Kiran Naqvi is currently running

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SNDX-5613 + Chemotherapy

for Acute Myeloid Leukemia

This phase Ib trial tests the safety, side effects, and best dose of SNDX-5613 when given in combination with the standard chemotherapy treatment (daunorubicin and cytarabine) in treating patients with newly diagnosed acute myeloid leukemia that has changes in the NPM1 gene or MLL/KMT2A gene. SNDX-5613 blocks signals passed from one molecule to another inside cancer cells that are needed for cancer cell survival. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Adding SNDX-5613 to the standard chemotherapy treatment may be able to shrink or stabilize the cancer for longer than the standard chemotherapy treatment alone.

Recruiting

1 award

Phase 1

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Iadademstat + Venetoclax + Azacitidine

for Acute Myeloid Leukemia

This phase I trial tests safety, side effects and best dose of iadademstat with azacitidine and venetoclax for the treatment of patients with acute myeloid leukemia (AML) who have not received treatment (treatment naive). Chemotherapy drugs, such as iadademstat and azacitidine work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Giving iadademstat with azacitidine and venetoclax may be safe and tolerable in treating patients with treatment naive AML.

Recruiting

1 award

Phase 1

5 criteria

More about Kiran Naqvi

Clinical Trial Related

1 year of experience running clinical trials · Led 5 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Kiran Naqvi has experience with

  • Venetoclax
  • Arsenic Trioxide
  • Gemtuzumab Ozogamicin
  • Tretinoin
  • Cytarabine
  • Milademetan Tosylate

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