Prof. Ki-hyeong Lee of the hematology ...

Dr. Ki Hyeong Lee

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Chungbuk National University Hospital

Expert in Lung Cancer
Studies Non-Small Cell Lung Cancer
17 reported clinical trials
26 drugs studied

Area of expertise

1Lung Cancer
Global Leader
Ki Hyeong Lee has run 13 trials for Lung Cancer. Some of their research focus areas include:
Stage IV
Stage III
EGFR positive
2Non-Small Cell Lung Cancer
Ki Hyeong Lee has run 8 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:
Stage III
Stage IV
PD-L1 positive

Affiliated Hospitals

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AdventHealth

Clinical Trials Ki Hyeong Lee is currently running

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Fianlimab + Cemiplimab

for Non-Small Cell Lung Cancer

This trial is testing a new drug combination for patients with advanced lung cancer. It aims to see if using two drugs together is more effective than one alone. The study also looks at side effects, how the drugs are processed in the body, and their impact on quality of life.
Recruiting0 awards Phase 2 & 3
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JIN-A02

for Non-Small Cell Lung Cancer

This study is a Phase I/II open-label, multi-center study to evaluate the safety, tolerability, PK, and an anti-tumor activity of JIN-A02, a 4th generation EGFR-TKI agent for oral administration, in EGFR mutant-positive, advanced NSCLC subjects who showed disease progression after receiving standard anticancer therapy, including approved EGFR-TKI therapy and/or no more than a single platinum-based anticancer chemotherapy. In Part A of the study, dose escalation is carried out where MTD is evaluated using Bayesian Optimal Interval (BOIN) design in subjects with advanced NSCLC harboring EGFR-mutation of C797S or T790M. In Part B, dose exploration is carried out to further evaluate the safety of JIN-A02 and to determine the RP2D using 2 preliminary effective dose levels and with the help of a safety review committee (SRC) in advanced NSCLC subjects harboring EGFR mutant C797S or T790M. In Part C dose expansion study, subjects with EGFR mutant who show disease progression after receiving standard anticancer therapy, including approved EGFR-TKI therapy with activity against T790M such as Osimertinib and/or no more than one platinum-based anticancer chemotherapy, are divided into 5 different cohorts based on the EGFR mutation and the anti-tumor activity of JIN-A02 is evaluated. Before enrollment in the study, the EGFR mutant profile is determined using either tumor tissue and/or plasma ctDNA. The profile is determined locally through a test method approved by the sponsor. The sponsor reviews and approves each potential subject for enrollment. Study eligibility evaluation will utilize local test(s).
Recruiting1 award Phase 1 & 212 criteria

More about Ki Hyeong Lee

Clinical Trial Related2 years of experience running clinical trials · Led 17 trials as a Principal Investigator · 10 Active Clinical Trials
Treatments Ki Hyeong Lee has experience with
  • Cisplatin
  • Pemetrexed
  • Pembrolizumab
  • Docetaxel
  • Carboplatin
  • Cemiplimab

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