Kerrie Moreau | VA Eastern Colorado ...

Dr. Kerrie L Moreau, PhD

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University of Colorado CCTSI CTRC

Studies Menopause
Studies Aging
6 reported clinical trials
16 drugs studied

Affiliated Hospitals

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University Of Colorado Anschutz Medical Campus

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University Of Colorado CCTSI CTRC

Clinical Trials Kerrie L Moreau, PhD is currently running

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NightWare

for PTSD

The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans with nightmares related to posttraumatic stress disorder (PTSD). The investigators also want to learn whether it improves cardiovascular health among this population.

Recruiting

0 awards

N/A

2 criteria

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Estradiol Patch

for Menopause

The menopause transition is associated with a decrease in artery health and an increased risk for weight gain in storing fat in the stomach area which may increase the risk for heart disease. The purpose of this research is to study how the decrease in estrogen at menopause changes artery health and fat gain, and risk of disease in women as they age. The first aim in this study will determine whether short term and long term low estrogen levels in premenopausal women decreases artery function and whether this is related to an increase in fat in the stomach area. The second aim will determine whether the changes in artery health and body fat are related to changes in a pathway that breaks down an important amino acid called tryptophan. This pathway is thought to play a role in regulating the aging process. Therefore, the investigators will determine whether the decrease in artery health and the increase in body fat in the stomach region with low estrogen is related to changes in this pathway in the blood, in vascular cells and fat tissue. Because estrogen levels fluctuate in premenopausal women, the investigators will use an approach (intervention) that controls estrogen levels to address these aims. The investigators will use a medication that is typically used to treat endometriosis or uterine fibroids to lower estrogen levels and an estrogen patch to increase estrogen in some women. Some women will receive a patch that has no estrogen (called a placebo patch). The intervention period will be 20 weeks. The study will provide us with new knowledge on how low estrogen with menopause affects artery health and fat gain estrogen.

Recruiting

2 awards

Phase 4

More about Kerrie L Moreau, PhD

Clinical Trial Related

3 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Kerrie L Moreau, PhD has experience with

  • NightWare
  • Degarelix
  • Transdermal Estradiol Patch
  • Transdermal Placebo Patch
  • Acyline
  • Arimidex

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