Kelsey Klute, MD | Department of ...

Dr. Kelsey Klute, MD

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University of Nebraska Medical Center

Studies Pancreatic Cancer
Studies Pancreatic Cyst
7 reported clinical trials
10 drugs studied

Area of expertise

1

Pancreatic Cancer

Kelsey Klute, MD has run 5 trials for Pancreatic Cancer. Some of their research focus areas include:

Stage III
Stage IV
2

Pancreatic Cyst

Kelsey Klute, MD has run 2 trials for Pancreatic Cyst. Some of their research focus areas include:

Stage I
Stage II

Affiliated Hospitals

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University Of Nebraska Medical Center

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Nebraska Medicine-Nebraska Medical Center

Clinical Trials Kelsey Klute, MD is currently running

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Tamoxifen

for Pancreatic Cysts

Pancreatic mucinous cystic neoplasm (MCN) is a precursor to invasive pancreatic adenocarcinoma which occurs almost exclusively in females in their 5th-7th decade. Currently the only option for MCN treatment and prevention of invasive pancreatic ductal adenocarcinoma (PDA) is oncologic resection. The clinical features of pancreatic MCN support the influence of sex hormones in the pathogenesis of the disease. Anti-hormonal therapy may therefore constitute an effective approach to treatment. Preliminary analyses from preclinical studies suggest that tamoxifen inhibits the spread and normal life cycle in MCN epithelial cells and fibroblasts. Investigators hypothesize that in humans, treatment with tamoxifen will lead to cyst regression or stabilization and may spare or delay the need for resection. Up to 15 participants not undergoing immediate resection will be enrolled and take tamoxifen orally for up to 24 weeks. The study will assess the feasibility of tamoxifen as a treatment for pancreatic MCN.

Recruiting

1 award

Phase 1

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Early Detection

for Pancreatic Cancer

The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multisite cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked to PDAC risk for longitudinal follow up.

Recruiting

1 award

N/A

10 criteria

More about Kelsey Klute, MD

Clinical Trial Related

2 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Kelsey Klute, MD has experience with

  • Gemcitabine
  • Nab-paclitaxel
  • Tamoxifen
  • None
  • Botensilimab
  • Heart Rate Monitoring

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