Dr. Justin Riddle, PhD

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Florida State University

Studies Major Depressive Disorder
Studies Social Anhedonia
2 reported clinical trials
6 drugs studied

Affiliated Hospitals

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Florida State University

Clinical Trials Justin Riddle, PhD is currently running

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tRAS Brain Stimulation

for Executive Dysfunction

Working memory (WM) is the ability to hold relevant information in mind in the absence of sensory input. The capacity for WM is a foundation for cognitive control and higher cognitive function more broadly. Previous research demonstrated that during the delay period of WM tasks, oscillatory electrical activity in the prefrontal cortex in the theta-frequency band (4-8 Hz) increased in amplitude. However, other groups found that the slope of the aperiodic signal in the brain was positively correlated with individual differences in WM capacity. Since low-frequency power and a steeper slope of the aperiodic signal are confounded in many analyses, it is not clear whether the slope of the aperiodic signal or the amplitude of low-frequency oscillations underlie WM capacity. With many studies investigating the causal role of theta oscillations in WM, the purpose of this project is to investigate the role of the aperiodic signal in WM performance.
Recruiting0 awards N/A6 criteria
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Brain Stimulation

for Depression

Anhedonia, the inability to seek-out and experience pleasure, is a common symptom in depression that predicts treatment-resistance and is sometimes exacerbated by first-line antidepressants. In our previous research, we found that anhedonia decreases goal-directed behavior and its related neural activity. In this study, we will investigate target engagement from five-consecutive days of stimulation for participants that are within a unipolar major depressive episode and also have high symptoms of anhedonia.
Recruiting0 awards N/A9 criteria

More about Justin Riddle, PhD

Clinical Trial Related1 year of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Justin Riddle, PhD has experience with
  • Delta-beta TACS
  • Sham TACS
  • Theta-gamma TACS
  • Flat-tRAS
  • Sham-tRAS
  • Steep-tRAS
Breakdown of trials Justin Riddle, PhD has run
Major Depressive Disorder

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