Dr. Jussi Nikkola
Claim this profileTampere University Hospital and Tampere University
Area of expertise
Transitional Cell Carcinoma
Jussi Nikkola has run 2 trials for Transitional Cell Carcinoma. Some of their research focus areas include:
Bladder Cancer
Jussi Nikkola has run 2 trials for Bladder Cancer. Some of their research focus areas include:
Clinical Trials Jussi Nikkola is currently running
Urine Tumor DNA Test
for Lynch Syndrome
Lynch syndrome (LS) is an inherited cancer predisposition syndrome caused by pathogenic germline variants in DNA mismatch repair (MMR) genes. New cancer screening and diagnostic tools are urgently needed to identify LS-related cancers early enough for curative treatment. Urothelial cancers (comprising bladder and upper tract urothelial tumors) are the third most common cancer after colorectal and endometrial cancers in individuals with LS. Up to one in four LS individuals will develop urothelial cancer during their lifetime, with the risk varying based on the defective MMR gene. In this clinical trial, we will employ urine tumor DNA (utDNA) to identify asymptomatic urothelial cancers in Lynch syndrome patients, and to investigate the potential benefits of urine tumor DNA based screening in this high-risk population.
Recruiting
1 award
N/A
Urine DNA Testing
for Bladder Cancer
Urothelial cancers of the bladder and upper urinary tract account for over 200,000 deaths and 600,000 diagnoses annually worldwide. The most common presenting symptom is hematuria (blood in urine), triggering a cascade of tests, including an invasive examination of the bladder using a flexible scope (cystoscopy). Millions of cystoscopies are performed every year worldwide for patients presenting with hematuria, but only 10% result in a cancer diagnosis. The UROSCOUT-1 trial is a prospective multicenter observational study that explores the potential of urine tumor DNA (utDNA) testing to replace a significant portion of cystoscopies in the diagnostic setting for hematuria or other reasons to rule out urothelial cancer. The goal is to enhance patient quality of life, reduce healthcare costs, and address increased workloads in urology centers. Sample collection will be conducted by mail, and the samples will be analyzed in a blinded manner, without knowledge of which patients are diagnosed with cancer. Random subsampling will be applied to cancer-negative patients to achieve an approximate 1:1 ratio between cancer-positive and -negative patients.
Recruiting
1 award
N/A
2 criteria
More about Jussi Nikkola
Clinical Trial Related
2 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Jussi Nikkola has experience with
- Urothelial Cancer Screening Using Urine Cytology
- Urothelial Cancer Screening Using Urine Tumor DNA Test
Breakdown of trials Jussi Nikkola has run
Transitional Cell Carcinoma
Cancer Syndromes
Urogenital Diseases
Lynch Syndrome
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Jussi Nikkola specialize in?
Jussi Nikkola focuses on Transitional Cell Carcinoma and Bladder Cancer. In particular, much of their work with Transitional Cell Carcinoma has involved MLH1 positive patients, or patients who are MSH2 positive.
Is Jussi Nikkola currently recruiting for clinical trials?
Yes, Jussi Nikkola is currently recruiting for 2 clinical trials in the USA. If you're interested in participating, you should apply.
Are there any treatments that Jussi Nikkola has studied deeply?
Yes, Jussi Nikkola has studied treatments such as Urothelial cancer screening using urine cytology, Urothelial cancer screening using urine tumor DNA test.
What is the best way to schedule an appointment with Jussi Nikkola?
Apply for one of the trials that Jussi Nikkola is conducting.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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