Dr. Julie-An Talano
Claim this profileMedical College of Wisconsin
Area of expertise
Acute Lymphoblastic Leukemia
Julie-An Talano has run 5 trials for Acute Lymphoblastic Leukemia. Some of their research focus areas include:
Burkitt Lymphoma
Julie-An Talano has run 3 trials for Burkitt Lymphoma. Some of their research focus areas include:
Affiliated Hospitals
Children's Hospital Of Wisconsin
Medical College Of Wisconsin
Clinical Trials Julie-An Talano is currently running
Stem Cell Transplant with Conditioning Regimen
for Blood Diseases
This phase II clinical trial studies how well treosulfan, thiotepa, fludarabine, and rabbit anti-thymocyte globulin (rATG) before donor stem cell transplantation works in treating patients with nonmalignant (non-cancerous) diseases. Hematopoietic cell transplantation has been shown to be curative for many patients with nonmalignant (non-cancerous) diseases such as primary immunodeficiency disorders, immune dysregulatory disorders, hemophagocytic lymphohistiocytosis, bone marrow failure syndromes, and hemoglobinopathies. Powerful chemotherapy drugs are often used to condition the patient before infusion of the new healthy donor cells. The purpose of the conditioning therapy is to destroy the patient's abnormal bone marrow which doesn't work properly in order to make way for the new healthy donor cells which functions normally. Although effective in curing the patient's disease, many hematopoietic cell transplantation regimens use intensive chemotherapy which can be quite toxic, have significant side effects, and can potentially be life-threatening. Investigators are investigating whether a new conditioning regimen that uses less intensive drugs (treosulfan, thiotepa, and fludarabine phosphate) results in new blood-forming cells (engraftment) of the new donor cells without increased toxicities in patients with nonmalignant (non-cancerous) diseases.
Recruiting
1 award
Phase 2
8 criteria
Blinatumomab + HCT
for Acute Lymphoblastic Leukemia
This trial will assess the feasibility of alpha/beta T-cell and B-cell depleted allogeneic hematopoietic cell transplantation (HCT) followed by blinatumomab therapy for high-risk B cell acute lymphoblastic leukemia (ALL) as a means of reducing rates of subsequent relapse and improving survival, while also minimizing treatment-related morbidity/ mortality and late effects. The conditioning regimens will be dependent on the patient's minimal residual disease (MRD) status prior to HCT using high throughput sequencing.
Recruiting
2 awards
Phase 2
14 criteria
More about Julie-An Talano
Clinical Trial Related
6 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Julie-An Talano has experience with
- Tisagenlecleucel
- CliniMACS
- Peripheral Blood Stem Cell Transplantation
- Etoposide
- Dexamethasone
- Ruxolitinib
Breakdown of trials Julie-An Talano has run
Acute Lymphoblastic Leukemia
Burkitt Lymphoma
Relapse
Leukemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Julie-An Talano specialize in?
Julie-An Talano focuses on Acute Lymphoblastic Leukemia and Burkitt Lymphoma. In particular, much of their work with Acute Lymphoblastic Leukemia has involved CD19 positive patients, or patients who are CD20 positive.
Is Julie-An Talano currently recruiting for clinical trials?
Yes, Julie-An Talano is currently recruiting for 2 clinical trials in Milwaukee Wisconsin. If you're interested in participating, you should apply.
Are there any treatments that Julie-An Talano has studied deeply?
Yes, Julie-An Talano has studied treatments such as Tisagenlecleucel, CliniMACS, Peripheral Blood Stem Cell Transplantation.
What is the best way to schedule an appointment with Julie-An Talano?
Apply for one of the trials that Julie-An Talano is conducting.
What is the office address of Julie-An Talano?
The office of Julie-An Talano is located at: Medical College of Wisconsin, Milwaukee, Wisconsin 53226 United States. This is the address for their practice at the Medical College of Wisconsin.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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