Dr. John Villano, MD, PhD
Claim this profileUniversity of Kentucky/Markey Cancer Center
Studies Brain Tumor
Studies Cancer
21 reported clinical trials
37 drugs studied
About John Villano, MD, PhD
Education:
- Holds an MD (Doctor of Medicine).
- Earned a PhD (Doctor of Philosophy).
Experience:
- Serves as a Medical Oncologist specializing in brain cancer treatment at the University of Kentucky/Markey Cancer Center.
- Active member of the Medical Oncology Division at Markey Cancer Center, recognized as a Comprehensive Cancer Center by the National Cancer Institute.
- Engages in teaching medical students, residents, and fellows at the Markey Cancer Center.
Area of expertise
1Brain Tumor
Stage IV
IDH positive
1p/19q co-deletion positive
2Cancer
Stage IV
MLH-1 negative
MSH-2 negative
Affiliated Hospitals
Clinical Trials John Villano, MD, PhD is currently running
Multiple Targeted Therapies
for Meningioma
This trial studies four drugs to treat patients with worsening meningioma. These drugs work by blocking enzymes that the tumor cells need to grow. The trial focuses on patients whose tumors have specific genetic mutations.
Recruiting1 award Phase 210 criteria
Lomustine + Standard Therapy
for Glioblastoma
This phase III trial compares the effect of adding lomustine to standard chemotherapy with temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. MGMT methylated tumors are more likely to respond to temozolomide chemotherapy. Temozolomide is in a class of medications called alkylating agents. It works by damaging the cell's DNA and may kill tumor cells and slow down or stop tumor growth. Lomustine is a chemotherapy drug and in a class of medications called alkylating agents. It damages the cell's DNA and may kill tumor cells. Radiation therapy uses high energy x-ray photons to kill tumor cells and shrink tumors. Adding lomustine to standard chemotherapy with temozolomide and radiation therapy may shrink or stabilize glioblastoma.
Recruiting2 awards Phase 34 criteria
More about John Villano, MD, PhD
Clinical Trial Related6 years of experience running clinical trials · Led 21 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments John Villano, MD, PhD has experience with
- Nivolumab
- Pembrolizumab
- Radiation Therapy
- Lomustine
- Temozolomide
- Carboplatin
Breakdown of trials John Villano, MD, PhD has run
Brain Tumor
Cancer
- Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab
- Pembrolizumab + Chemotherapy for Brain Metastases from Lung Cancer
- Targeted Therapy for Brain Cancer
Lung Cancer
- Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab
- Radiation + Immunotherapy for Non-Small Cell Lung Cancer
- Pembrolizumab + Chemotherapy for Brain Metastases from Lung Cancer
Glioblastoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does John Villano, MD, PhD specialize in?
John Villano, MD, PhD focuses on Brain Tumor and Cancer. In particular, much of their work with Brain Tumor has involved Stage IV patients, or patients who are IDH positive.
Is John Villano, MD, PhD currently recruiting for clinical trials?
Yes, John Villano, MD, PhD is currently recruiting for 7 clinical trials in Lexington Kentucky. If you're interested in participating, you should apply.
Are there any treatments that John Villano, MD, PhD has studied deeply?
Yes, John Villano, MD, PhD has studied treatments such as Nivolumab, Pembrolizumab, Radiation Therapy.
What is the best way to schedule an appointment with John Villano, MD, PhD?
Apply for one of the trials that John Villano, MD, PhD is conducting.
What is the office address of John Villano, MD, PhD?
The office of John Villano, MD, PhD is located at: University of Kentucky/Markey Cancer Center, Lexington, Kentucky 40536 United States. This is the address for their practice at the University of Kentucky/Markey Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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