Dr. John M. Burke, MD
Claim this profileRocky Mountain Cancer Centers - Aurora
Area of expertise
Lymphoma
John M. Burke, MD has run 5 trials for Lymphoma. Some of their research focus areas include:
Chronic Lymphocytic Leukemia
John M. Burke, MD has run 3 trials for Chronic Lymphocytic Leukemia.
Affiliated Hospitals
Rocky Mountain Cancer Centers-Aurora
Rocky Mountain Cancer Centers
Clinical Trials John M. Burke, MD is currently running
Cema-cel
for B-Cell Lymphoma
This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved a complete response or partial response suitable for observation, but who have minimal residual disease (MRD) as detected by the Foresight CLARITY™ Investigational Use Only (IUO) MRD test, powered by PhasED-Seq™. The purpose of the trial is to assess the efficacy and safety of consolidation with cemacabtagene ansegedleucel (cema-cel), an allogeneic CD19 CAR T product, as compared to standard of care observation. In this study, participants with MRD are randomized 1:1 to treatment with cema-cel or an observation arm. Treatment includes cema-cel following a lymphodepletion regimen of fludarabine and cyclophosphamide. Prior to August 2025, participants may also have received an anti-CD52 monoclonal antibody, ALLO-647, as part of their lymphodepletion regimen.
Recruiting
1 award
Phase 2
5 criteria
Pirtobrutinib
for Chronic Lymphocytic Leukemia
The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), who have received 1-3 lines of treatment including a covalent Bruton tyrosine kinase (BTK) inhibitor. The purpose of Part 2 of this study is to evaluate pirtobrutinib monotherapy in participants with treatment-naïve CLL/SLL with 17p deletions. Participation in Part 1 is expected to last approximately 3 years. Participation in Part 2 is expected to last up to 2 years.
Recruiting
1 award
Phase 2
6 criteria
More about John M. Burke, MD
Clinical Trial Related
13 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments John M. Burke, MD has experience with
- Brentuximab Vedotin
- Doxorubicin
- Nivolumab
- Dacarbazine
- Cyclophosphamide
- Prednisone
Breakdown of trials John M. Burke, MD has run
Lymphoma
Chronic Lymphocytic Leukemia
Central Nervous System Hodgkin Lymphoma
Hodgkin's Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does John M. Burke, MD specialize in?
John M. Burke, MD focuses on Lymphoma and Chronic Lymphocytic Leukemia. In particular, much of their work with Lymphoma has involved CD30 negative patients, or patients who are HTLV-1 positive.
Is John M. Burke, MD currently recruiting for clinical trials?
Yes, John M. Burke, MD is currently recruiting for 2 clinical trials in Aurora Colorado. If you're interested in participating, you should apply.
Are there any treatments that John M. Burke, MD has studied deeply?
Yes, John M. Burke, MD has studied treatments such as Brentuximab Vedotin, Doxorubicin, Nivolumab.
What is the best way to schedule an appointment with John M. Burke, MD?
Apply for one of the trials that John M. Burke, MD is conducting.
What is the office address of John M. Burke, MD?
The office of John M. Burke, MD is located at: Rocky Mountain Cancer Centers - Aurora, Aurora, Colorado 80012 United States. This is the address for their practice at the Rocky Mountain Cancer Centers - Aurora.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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