Dr. Jennifer C Naylor, PhD

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Durham VA Medical Center, Durham, NC

Studies Chronic Persistent Surgical Pain
Studies Depression
3 reported clinical trials
3 drugs studied

Affiliated Hospitals

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Durham VA Medical Center, Durham, NC

Clinical Trials Jennifer C Naylor, PhD is currently running

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Pregnenolone

for Anxiety and Depression

Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to successfully form and maintain valued relationships. Several other symptoms commonly occur with anxiety and depression, including poor sleep quality and chronic pain. Since all these symptoms frequently occur together, they may have a common underlying biological basis. A single medication that could effectively treat all these symptoms would be ideal. Converging data suggest that pregnenolone is a promising pharmacological agent for treating multiple psychiatric symptoms and functional impairment. The investigators thus propose to conduct a clinical trial of pregnenolone in Veterans with anxiety and depression symptoms. Pregnenolone has minimal side effects, and the prior research demonstrates that pregnenolone is well-tolerated by Veterans. Treatment with pregnenolone could thus be an efficacious new therapeutic for Veterans experiencing depression, anxiety, poor sleep quality and chronic pain conditions.

Recruiting

0 awards

Phase 2

More about Jennifer C Naylor, PhD

Clinical Trial Related

1 year of experience running clinical trials · Led 3 trials as a Principal Investigator · 1 Active Clinical Trial

Treatments Jennifer C Naylor, PhD has experience with

  • Pregnenolone
  • DHEA
  • Placebo

Breakdown of trials Jennifer C Naylor, PhD has run

Chronic Persistent Surgical Pain

Depression

Post-Traumatic Stress Disorder

Chronic Lower Back Pain

Anxiety Disorders

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