Dr. Jennifer Flythe, MD

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University of North Carolina at Chapel Hill

Studies Chronic Renal Failure
Studies Kidney Failure
3 reported clinical trials
8 drugs studied

Affiliated Hospitals

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University Of North Carolina At Chapel Hill
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University Of North Carolina, Chapel Hill

Clinical Trials Jennifer Flythe, MD is currently running

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Incremental Hemodialysis Frequency

for Kidney Failure

This study is to prospectively compare clinical effectiveness between clinically- matched incremental hemodialysis and conventional hemodialysis in patients with incident kidney dysfunction requiring dialysis and residual kidney function. The study will enroll 350 patients on chronic hemodialysis and 140 caregivers of enrolled patients. Patients will be randomized in 1:1 ratio to either incremental start hemodialysis or conventional hemodialysis. Caregivers will be followed along with patients for an average period of 2 years post randomization.
Recruiting1 award N/A5 criteria
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Symptom Monitoring

for Kidney Failure

The SMaRRT-HD trial is a cluster randomized trial of symptom monitoring with supported clinician follow-up using the SMaRRT-HD electronic patient reported outcome measure (ePROM) system versus Usual Care. Approximately 2400 patients at up to 36 geographically and racially diverse US hemodialysis clinics will be enrolled. The primary trial hypothesis is that regular symptom patient reported outcome measure (PROM) administration with supported clinician follow-up in dialysis care will reduce suffering and improve outcomes by prompting treatment of unrecognized symptoms, and enhancing patient-care team communication. Clinics randomized to the SMaRRT-HD group will adopt the use of SMaRRT-HD for 12 months. SMaRRT-HD is a symptom monitoring system that includes 1) tablet-based symptom reporting using a PROM and 2) supported clinician follow-up consisting of symptom alerts, guidances for symptom management, and symptom tracking reports that are shared with patients. Dialysis clinics randomized to Usual Care will not adopt SMaRRT-HD or any other trial-driven procedures. Usual Care clinics will monitor symptoms through clinical care interactions with participants and by administering a Health Related Quality of Life survey that includes questions about symptoms.
Recruiting1 award N/A3 criteria

More about Jennifer Flythe, MD

Clinical Trial Related1 year of experience running clinical trials · Led 3 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Jennifer Flythe, MD has experience with
  • Usual Care
  • Symptom Monitoring On Renal Replacement Therapy - Hemodialysis (SMaRRT-HD)
  • Educational Materials
  • Motivational Interviewing
  • Conventional Hemodialysis
  • Hemodialysis Thrice Weekly

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