Jason T. Rich, MD - Otolaryngology–Head ...

Dr. Jason Rich, M.D.

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Washington University School of Medicine

Studies Squamous Cell Carcinoma
Studies Neck Cancer
6 reported clinical trials
11 drugs studied

Area of expertise

1Squamous Cell Carcinoma
Jason Rich, M.D. has run 3 trials for Squamous Cell Carcinoma. Some of their research focus areas include:
Stage III
p16 positive
p16 negative
2Neck Cancer
Jason Rich, M.D. has run 2 trials for Neck Cancer. Some of their research focus areas include:
Stage III
HPV negative
Stage IV

Affiliated Hospitals

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Washington University School Of Medicine

Clinical Trials Jason Rich, M.D. is currently running

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Chemotherapy and Radiation

for Cutaneous Angiosarcoma

Angiosarcoma is a rare and aggressive form of soft tissue sarcoma. Prior work demonstrates very poor outcomes, with most patients developing metastatic disease and less than 50% surviving greater than 5 years. In other soft tissue sarcomas, the use of radiotherapy and/or chemotherapy have improved progression-free survival in patients undergoing limited, organ-sparing surgeries. Taxane chemotherapy has shown efficacy in patients with metastatic angiosarcoma, but this has not been tested in patients with localized disease. This study examines the efficacy of induction paclitaxel followed by concurrent chemoradiation therapy with paclitaxel prior to curative surgical resection.
Recruiting1 award Phase 1 & 27 criteria
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Radiation, Cisplatin, and Surgery

for Throat Cancer

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer. Oropharynx SCC (OPSCC) is a common sub-type of HNSCC. Each year, 16,000 new cases of OPSCC are diagnosed in the USA. Most cases of OPSCC (\>90%) are caused by the human papillomavirus (HPV) and are often cured with current therapy. However, patients treated with surgery followed by postoperative adjuvant chemotherapy and radiation therapy (POA(C)RT) still experience substantial morbidity. In this highly curable disease, current clinical research interest is focused on investigation of de-escalated therapy, with the goal to reduce treatment-related adverse events (AEs) while maintaining a low recurrence rate. In this study, patients with HPV-related OPSCC will undergo resection of the primary tumor site and involved/at-risk regional neck nodes. Based on the pathology report, patients will be assigned to: * Arm 1 (de-POACRT-42 Gy) * Arm 2A (de-POART-42 Gy) * Arm 2B (de-POART-37.8 Gy) * Arm 2C (de-POACRT-30 Gy). All patients with high-risk pathology will be assigned to Arm 1 whereas patients with intermediate-risk pathology will be randomized (1:1:1) to Arm 2A, Arm 2B, or Arm 2C. Patients with highest-risk pathology and low-risk pathology will be removed from the trial after surgery and will be advised to pursue standard of care options.
Recruiting1 award Phase 26 criteria

More about Jason Rich, M.D.

Clinical Trial Related7 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Jason Rich, M.D. has experience with
  • Cisplatin
  • Radiation Therapy
  • CareOrbit
  • Cetuximab
  • Intensity-Modulated Radiation Therapy
  • Palbociclib

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