Dr. Isabella Soreca, MD
Claim this profileVA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Studies Apnea
Studies Obstructive Sleep Apnea Syndrome
3 reported clinical trials
6 drugs studied
Affiliated Hospitals
Clinical Trials Isabella Soreca, MD is currently running
Bright Light Therapy
for Sleep Apnea
Persistent daytime symptoms of sleepiness in individuals with obstructive sleep apnea (OSA) who are using Continuous Positive Airway Pressure (CPAP) are associated with adverse long term medical and functional outcomes. Supplementary exposure to bright light has beneficial effects on sleep quality and daytime vigilance in healthy individuals and it has been increasingly applied in a variety of sleep and neuropsychiatric conditions. This study will explore the role of Bright Light Therapy (BLT), a well-established non-pharmacological intervention for circadian disturbances, for the treatment of residual daytime symptoms of OSA which do not respond to CPAP. BLT will be delivered via therapy glasses in a cross-over design, where each participant will be exposed to active treatment and sham treatment (4 weeks in each arm) in a randomized order. The hypothesis is that participants will demonstrate improvements in the variables of interest during the four-week active treatment portion of the eight-week crossover study, compared to the four-week sham treatment portion.
Recruiting0 awards N/A5 criteria
Medications
for PTSD-Related Insomnia
Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone or eszopiclone can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memories, difficulty sleeping, poor concentration, irritability, anger, and emotional withdrawal. Insomnia is a disorder that can make it hard to fall sleep, stay asleep or cause a person to wake up too early and not be able to fall back to sleep.
Recruiting1 award Phase 32 criteria
More about Isabella Soreca, MD
Clinical Trial Related1 year of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Isabella Soreca, MD has experience with
- Bright Light Therapy (BLT)
- Eszopiclone
- Gabapentin
- Placebo
- Trazodone
- Bright Light Therapy
Breakdown of trials Isabella Soreca, MD has run
Apnea
Obstructive Sleep Apnea Syndrome
Sleep Apnea
Obstructive Sleep Apnea
Insomnia
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